产品名称
单克隆抗-微管蛋白,酪氨酸 小鼠抗, clone TUB-1A2, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
TUB-1A2, monoclonal
contains
15 mM sodium azide
species reactivity
human, plant, animal
technique(s)
indirect immunofluorescence: 1:800 using cultured chicken fibroblasts
microarray: suitable
western blot: suitable
isotype
IgG3
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TUBA4A(7277), TUBB(203068)
Application
单克隆抗酪氨酸微管蛋白用于:
- 间接免疫荧光标记
- 免疫印迹技术
- 免疫细胞化学染色
Biochem/physiol Actions
微管蛋白是微管的主要构建单元。微管蛋白的组装过程涉及微管蛋白酪氨酸化。特异性微管蛋白酪氨酸羧肽酶去除末端酪氨酸,产生末端为谷氨酸残基的 α-微管蛋白;而另一种酶通过在羧基末端添加酪氨酸修饰 α-微管蛋白,从而形成酪氨酸增加和损失的潜在循环。
该抗体在免疫印迹测定中与微管蛋白的C-末端酪氨酸反应,可用于培养细胞或组织切片中该表位的定位。
Disclaimer
除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
General description
单克隆抗络氨酸微管蛋白(小鼠 IgM 同种型)来源于杂交瘤,该杂交瘤由小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生。微管蛋白为圆柱形丝状结构,几乎存在于所有真核细胞中。微管蛋白是异二聚体,由 α-微管蛋白和 β-微管蛋白组成。 每种亚基的分子量均为55 kDa,具有相当大的同源性。
微管,是细胞内圆柱状丝状结构,主要由微管蛋白组成,存在于所有真核细胞中。单克隆抗酪氨酸抗体可通过间接免疫荧光标记,对酪氨酸 α 微管蛋白进行免疫细胞化学定位。 单克隆抗酪氨酸抗体与酪氨酸微管蛋白发生特异性反应,适用于牛脑细胞、非洲绿猴肾细胞(Vero),犬肾细胞(MDCK)、袋鼠肾细胞(Potoroo,PtK2)、小鼠垂体瘤细胞(AtT-20)、酵母细胞和非洲爪蟾细胞。
Immunogen
含有 α-微管蛋白羧基端氨基酸的肽
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
法规信息
常规特殊物品
此项目有
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Mayorova TD, et al.
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Microtubule Structures
Molecular Cell Biology. 4th edition. (2000)
L J Lee et al.
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商品
Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.
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