T8691
牛磺酸
suitable for cell culture, BioXtra, meets USP testing specifications
别名:
2-氨基乙磺酸
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关于此项目
线性分子式:
NH2CH2CH2SO3H
化学文摘社编号:
分子量:
125.15
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
203-483-8
MDL number:
Beilstein/REAXYS Number:
1751215
产品名称
牛磺酸, suitable for cell culture, meets USP testing specifications
InChI key
XOAAWQZATWQOTB-UHFFFAOYSA-N
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
SMILES string
NCCS(O)(=O)=O
agency
meets USP testing specifications
product line
BioXtra
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
>300 °C (lit.)
Quality Level
Gene Information
rat ... Ppm1a(24666)
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Application
牛磺酸已用于以下情形：
- 作为心肌细胞解离溶液的组分
- 作为改性合成输卵管液(m-SOF)培养基的补充剂，用于培养假定的受精卵
- 作为低Ca2+溶液的组成部分，用于制备胶原酶B溶液，将菌落分解成单个细胞
- 在体外受精过程中评估与不同牛精子受精后对牛胚胎发育的影响
- 作为角膜类器官衍生培养基的组分
Biochem/physiol Actions
牛磺酸主要存在于视网膜和心脏，也存在于脑、肠、骨骼肌和肾中。牛磺酸可以调节细胞内钙浓度，防止缺血再灌注损伤并具有降血压特性。牛磺酸还在胆汁形成和脂肪消化中发挥作用。牛磺酸缺乏与焦虑、多动、癫痫和抑郁有关。
甘氨酸受体的非选择性内源激动剂。
甘氨酸受体的非选择性内源激动剂。在某些细胞中调节细胞凋亡的条件必需磺化氨基酸；在许多新陈代谢活动中起作用；是蛋氨酸和半胱氨酸的代谢产物。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells
Zanella F and Sheikh F
Methods in Molecular Biology, 147-162 (2014)
Cornea organoids from human induced pluripotent stem cells
Foster JW, et al.
Scientific Reports, 7 (2017)
The Effect of Various Concentrations of Taurine during In vitro Fertilization on the Development of Bovine Embryos Fertilized with Spermatozoa from Three Different Bulls
Tsuzuki Y, et al.
Asian-Australasian Journal of Animal Sciences (2010)
Variations in bovine embryo production between individual donors for OPU-IVF are closely related to glutathione concentrations in oocytes during in vitro maturation
Hidaka T, et al.
Theriogenology, 113(2), 176-182 (2018)
Scalable expansion of human pluripotent stem cells in suspension culture
Zweigerdt R, et al.
Nature Protocols, 6(5), 689-689 (2011)
商品
Ultrapure water from Milli-Q® system shown free of BPA, suitable for embryology research, minimizing endocrine disruptor interference.
Milli-Q® 系统产出的超纯水不含BPA，适合用于胚胎学研究，最大限度地减少内分泌干扰物的干扰。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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