一般描述
应用
- 溶解在CaCl2 中，并添加到聚乙二醇化的纤维蛋白原/细胞溶液中以生产纤维蛋白
- 在孔板上聚合纤维蛋白
- 用作蛋白酶激活受体的内源性激动剂蛋白酶：刺激细胞的PAR1、PAR3和PAR4
生化/生理作用
单位定义
外形
分析说明
其他说明
免责声明
底物
警示用语：
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the cross reactivity of Thrombin?
Thrombin from any vertebrate species will clot the fibrinogen of virtually any other species. Fibrinogen from any mammalian source will cross-react with thrombin from any mammalian source, but it is not well known how thrombin and fibrinogen from different animals differ in their sequence. When any mammalian thrombin is injected into a different mammal, clotting will occur.
For thrombin, how do NIH units compare to International Units (IU)?
One NIH unit of thrombin is equivalent to approximately 1.8 International Unit (IU) of thrombin.
What is the solubility of Product T7009, Thrombin from human plasma?
Thrombin from human plasma gave a clear very faint yellow solution when dissolved at 100 unit vial plus 1 ml of 28 mM sodium barbital, 0.125M sodium chloride, 1% BSA, 0.5% PEG, pH 7.35. Thrombin from bovine plasma (T4648) is soluble in water at 10 mg/mL.
What is the solution stability of Product T7009, Thrombin from human plasma?
By analogy to thrombin from bovine plasma (T4648), we expect stock solutions of thrombin from human plasma to be stable for one week kept refrigerated at 2-8° C. Since thrombin solutions adsorb to glass, it is recommended to aliquot the solutions in plastic tubes and store frozen at -20°C or colder for long term storage.
What is the isoelectric point of Product T7009, Thrombin from human plasma?
The isoelectric point (pI) range of the human thrombin isozymes is 6.35 - 7.6. The major isoform has a pI of 7.31.
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商品
凝血酶因子IIa是一种内切丝氨酸蛋白酶，可选择性地裂解纤维蛋白原的Arg -Gly键，形成纤维蛋白并释放纤维蛋白肽A和B。
Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.
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