产品名称
单克隆抗肌钙蛋白 T 小鼠抗, clone JLT-12, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
JLT-12, monoclonal
contains
15 mM sodium azide
species reactivity
chicken, rat, bovine, rabbit
technique(s)
immunohistochemistry: suitable
western blot: 1:200 using rabbit total skeletal muscle extract
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Tnnt1(171409), Tnnt2(24837), Tnnt3(24838)
Application
小鼠抗肌钙蛋白 T 单克隆抗体可用于以下研究：
- 免疫印迹分析。
- 免疫细胞化学分析。
- 免疫荧光。
小鼠抗肌钙蛋白 T 单克隆抗体可用于免疫染色。
Biochem/physiol Actions
肌钙蛋白T是肌钙蛋白的亚基，可促进肌钙蛋白与原肌球蛋白的结合。它在肌肉收缩中也起着至关重要的作用。心肌肌钙蛋白T是检测急性心肌梗死（MI）的潜在标志物。除了促进肌钙蛋白组分与肌动蛋白-原肌球蛋白丝的结合外，它还在调节肌动蛋白ATP酶活性方面发挥着重要作用。心肌肌钙蛋白T基因突变会导致肥厚型心肌病。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
单克隆抗肌钙蛋白T（小鼠 IgG1 同种型）来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。
肌钙蛋白T是肌钙蛋白的重要亚基。肌钙蛋白T是一种逗号状或棒状蛋白，长度为185-205 Å。肌钙蛋白T位于肌动蛋白螺旋沟（helix groove）中，并延伸至肌动蛋白丝。血清肌钙蛋白T的寿命为120分钟。该蛋白的N-末端富含带负电荷的残基，C-末端富含带正电荷的残基。肌钙蛋白T中不均匀的电荷分布有助于其在生理盐浓度下的聚集。在人体内，心脏肌钙蛋白T有四种亚型，其中的三种在胚胎中表达，一种亚型在成年心脏中表达。
Immunogen
来自兔骨骼肌的肌钙蛋白 T。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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