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主要文件

安全信息

T5319

Sigma-Aldrich

Tetanolysin from Clostridium tetani

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选择尺寸

0.1 MG
CN¥2,463.91

CN¥2,463.91


国内现货,预计发货时间April 16, 2025详情



选择尺寸

变更视图
0.1 MG
CN¥2,463.91

About This Item

MDL编号:
UNSPSC代码:
12352200

CN¥2,463.91


国内现货,预计发货时间April 16, 2025详情


生物来源

Clostridium tetani E88

分子量

55 kDa

应用

cell analysis

储存温度

2-8°C

基因信息

Clostridium tetani E88 ... CTC01888(1060232)

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此商品
V8379F0556CC130
玻连蛋白 from human plasma, suitable for cell culture, solution

5051

玻连蛋白

biological source

human plasma

biological source

human plasma

biological source

human fibroblasts

biological source

Escherichia coli, human

sterility

sterile-filtered

sterility

-

sterility

sterile-filtered

sterility

-

assay

>95%

assay

-

assay

-

assay

≥92% (SDS-PAGE)

concentration

0.5 mg/mL

concentration

-

concentration

~0.5 mg/mL

concentration

0.5 mg/mL

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

100

一般描述

Hemolytic activity of tetanolysin is determined using 2.5% rabbit red blood cells at 37 °C for 40 min.

应用

Tetanolysin has been used to analyze the formation of lytic pores in red blood cells (RBCs)1. It has also been used to permeabilize infected RBCs2.

生化/生理作用

Cholesterol-binding toxin used to permeabilize cellular membranes to enhance the entry of macromolecules into the interior of the cell. Pores induced reported to be in the range of 20-50 nm.
Cholesterol-binding toxin used to permeabilize cellular membranes to enhance the entry of macromolecules into the interior of the cell..

制备说明

Prepared by a modification of the method of Haque, et al.

重悬

When reconstituted with 100 μl of sterile water the concentration is 1 μg/μl in 40 mM sodium phosphate buffer, pH 7.2, containing 200 mM NaCl.

分析说明

Single band by SDS-PAGE.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Hayley E Bullen et al.
    The Journal of biological chemistry, 287(11), 7871-7884 (2012-01-19)
    To survive within its host erythrocyte, Plasmodium falciparum must export hundreds of proteins across both its parasite plasma membrane and surrounding parasitophorous vacuole membrane, most of which are likely to use a protein complex known as PTEX (Plasmodium translocon of
    Jason W Rosch et al.
    The Journal of clinical investigation, 120(2), 627-635 (2010-01-23)
    Sickle cell disease (SCD) is characterized by intravascular hemolysis and inflammation coupled to a 400-fold greater incidence of invasive pneumococcal infection resulting in fulminant, lethal pneumococcal sepsis. Mechanistically, invasive infection is facilitated by a proinflammatory state that enhances receptor-mediated endocytosis

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