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文件

T4069

JC-1

Name: JC-1
Brand: SIGMA

≥97% purity, solid

别名:

5,5'，6,6′-四氯-1,1′,3,3′-四乙基-脒酞菁碘化物, 5,5'，6,6′-四氯-1,1′,3,3′-四乙基苯并咪唑碳氰碘化物, CBIC2（3）

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About This Item

经验公式（希尔记法）:

C₂₅H₂₇Cl₄IN₄

CAS号:

3520-43-2

分子量:

652.23

MDL编号:

MFCD00188475

UNSPSC代码:

12171500

PubChem化学物质编号:

24900193

NACRES:

NA.47

product name

JC-1, solid

检测方案

≥97%

质量水平

100

形式

solid

颜色

red

ε (消光系数)

≥175000 at 511-517 nm in methanol

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[I-].CCN1C(=C\C=C\c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)/N(CC)c4cc(Cl)c(Cl)cc14

InChI

1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1

InChI key

FYNNIUVBDKICAX-UHFFFAOYSA-M

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应用

花青染料 Jc-1已被用于确定线粒体跨膜电位。

双发射电位敏感探针，可用于测量线粒体膜电位。在低膜电位时，JC-1是一个绿色荧光（λ_ex 520nm）单体。在较高的电位下，JC-1形成带有红色荧光（λ_em 596nm）的“J-聚集体”，其表现出宽的激发和非常窄的发射光谱。JC-1的红色与绿色荧光的比率仅取决于膜电位，并且不受线粒体大小、形状或密度的影响。

CS0390

线粒体染色试剂盒, 1 kit sufficient for 40 tests (of 5 mL cell suspensions), 1 kit sufficient for 200 tests (of 1 mL cell suspensions)

CS0760

线粒体分离物染色试剂盒, 1 kit sufficient for 50 reactions (in a 2 mL cuvette), 1 kit sufficient for 1000 reactions (using 96 multiwell plates)

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Radiation-induced tumor cells death is the theoretical basis of tumor radiotherapy. Death signaling disorder is the most important factor for radioresistance. However, the signaling pathway(s) leading to radiation-triggered cell death is (are) still not completely known. To better understand the

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

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