主要文件

查看所有文档

T4069

JC-1

Name: JC-1
Brand: SIGMA

≥97% purity, solid

别名:

5,5′，6,6′-四氯-1,1′,3,3′-四乙基-脒酞菁碘化物, 5,5′，6,6′-四氯-1,1′,3,3′-四乙基苯并咪唑碳氰碘化物, CBIC2（3）

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₂₅H₂₇Cl₄IN₄

化学文摘社编号:

3520-43-2

分子量:

652.23

UNSPSC Code:

12171500

PubChem Substance ID:

24900193

NACRES:

NA.47

MDL number:

MFCD00188475

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

产品名称

JC-1, powder or solid (Crystals)

assay

≥97%

Quality Level

100

form

powder or solid (Crystals)

technique(s)

titration: suitable

color

faint red to very dark red

ε (extinction coefficient)

≥175000 at 511-517 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[I-].CCN1C(=C\C=C\c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)/N(CC)c4cc(Cl)c(Cl)cc14

InChI

1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1

InChI key

FYNNIUVBDKICAX-UHFFFAOYSA-M

说明

Application

花青染料 Jc-1已被用于确定线粒体跨膜电位。

双发射电位敏感探针，可用于测量线粒体膜电位。在低膜电位时，JC-1是一个绿色荧光（λ_ex 520nm）单体。在较高的电位下，JC-1形成带有红色荧光（λ_em 596nm）的“J-聚集体”，其表现出宽的激发和非常窄的发射光谱。JC-1的红色与绿色荧光的比率仅取决于膜电位，并且不受线粒体大小、形状或密度的影响。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

商品

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Apoptosis Assays

Cellular apoptosis assays to detect programmed cell death using Annexin V, Caspase and TUNEL DNA fragmentation assays.

凋亡分析检测

细胞凋亡测定使用膜联蛋白V、Caspase和TUNEL DNA片段化检测法检测程序性细胞死亡。

查看所有文章

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

A Perelman

Cell Death & Disease (2012)

Radiation induces apoptosis primarily through the intrinsic pathway in mammalian cells.

Xianbin Cao et al.

Cellular signalling, 62, 109337-109337 (2019-06-08)

Radiation-induced tumor cells death is the theoretical basis of tumor radiotherapy. Death signaling disorder is the most important factor for radioresistance. However, the signaling pathway(s) leading to radiation-triggered cell death is (are) still not completely known. To better understand the

Sulfated polysaccharide-protein complex sensitizes doxorubicin-induced apoptosis of breast cancer cells in vitro and in vivo

Jie Wang

Experimental and Therapeutic Medicine (2016)

查看所有相关文献

全球贸易项目编号

货号	GTIN
T4069-5MG	04061837345500