推荐产品
产品名称
JC-1, powder or solid (Crystals)
方案
≥97%
质量水平
表单
powder or solid (Crystals)
技术
titration: suitable
颜色
faint red to very dark red
ε (消光系数)
≥175000 at 511-517 nm in methanol
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[I-].CCN1C(=C\C=C\c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)/N(CC)c4cc(Cl)c(Cl)cc14
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应用
双发射电位敏感探针，可用于测量线粒体膜电位。 在低膜电位时，JC-1是一个绿色荧光（λex 520nm）单体。在较高的电位下，JC-1形成带有红色荧光（λem 596nm）的“J-聚集体”，其表现出宽的激发和非常窄的发射光谱。JC-1的红色与绿色荧光的比率仅取决于膜电位，并且不受线粒体大小、形状或密度的影响。
花青染料 Jc-1已被用于确定线粒体跨膜电位。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion
Li L
Cell Death & Disease (2016)
Shumin Qin et al.
Frontiers in pharmacology, 10, 894-894 (2019-09-03)
Alcohol consumption affects gastric mucosa by multiple and complex mechanisms depending either by direct contact of ethanol or by indirect biological damage induced by its metabolite acetaldehyde. The present study aims at further investigating the mechanism of ethanol-induced gastric mucosa
Qiong Wang et al.
Acta biomaterialia, 94, 469-481 (2019-05-30)
Multi-drug resistance (MDR) of tumor is a major cause of chemotherapy failure. In this study, a pH-sensitive graft copolymer, poly(β-amino ester)-g-β-cyclodextrin (PBAE-g-β-CD), was synthesized via Michael addition polymerization and was employed to co-deliver doxorubicin (DOX), a chemotherapy agent, and adjudin
Xianbin Cao et al.
Cellular signalling, 62, 109337-109337 (2019-06-08)
Radiation-induced tumor cells death is the theoretical basis of tumor radiotherapy. Death signaling disorder is the most important factor for radioresistance. However, the signaling pathway(s) leading to radiation-triggered cell death is (are) still not completely known. To better understand the
Sulfated polysaccharide-protein complex sensitizes doxorubicin-induced apoptosis of breast cancer cells in vitro and in vivo
Jie Wang
Experimental and Therapeutic Medicine (2016)
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