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Merck
CN

T3526

Sigma-Aldrich

抗-Tubulin 兔抗

whole antiserum

别名:

Anti-K-ALPHA-1

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

whole antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

包含

15 mM sodium azide

种属反应性

chicken, mouse

技术

indirect immunofluorescence: 1:80 using cultured fibroblasts
western blot: 1:200 using chicken gizzard extract or mouse brain extract

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

相关类别

一般描述

微管由微管蛋白和其他几种名为微管相关蛋白 (MAPs)的蛋白质组成。微管蛋白是一种异二聚体,由一条α-链和β-链所组成,而两者的分子量均约为55,000。微管在分裂间期可形成精细的细胞质网络,并在细胞分裂期间重组成有丝分裂纺锤体。
微管蛋白是一种极度保守的带负电荷的蛋白质。它可以在所有真核细胞中表达,不过主要在脑中表达。

特异性

此产品可对培养的鸡成纤维细胞或3T3小鼠成纤维细胞中的微管蛋白进行染色。在免疫印迹中可能会出现其他的染色条带。

免疫原

来自13天龄鸡胚大脑的微管蛋白

应用

兔抗微管蛋白抗体可用于免疫印迹和间接免疫荧光分析。

生化/生理作用

αβ-微管蛋白异源二聚体有助于形成微管。微管蛋白二聚体具有GTP酶活性、组装和分解性质。它能促进鞭毛器的构建。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: an in vitro model of HTLV-I-induced disease
Maldonado H, et al.
Biological Research, 41(3), 239-259 (2008)
Hong Zhu et al.
Experimental and therapeutic medicine, 15(3), 2643-2648 (2018-02-20)
The aim of the present study was to investigate the mechanism of action by which naringin reverses the resistance of ovarian cancer cells to cisplatin. Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) and western blotting assays were used to detect
Zhang Bao et al.
International journal of molecular medicine, 38(3), 823-833 (2016-07-20)
Mycobacterium tuberculosis (MTB), one of the major bacterial pathogens for lethal infectious diseases, is capable of surviving within the phagosomes of host alveolar macrophages; therefore, host genetic variations may alter the susceptibility to MTB. In this study, to identify host
K Schindowski et al.
Genes, brain, and behavior, 7 Suppl 1, 92-100 (2008-02-08)
The aim of the present study was to investigate the relation between neurogenesis, cell cycle reactivation and neuronal death during tau pathology in a novel tau transgenic mouse line THY-Tau22 with two frontotemporal dementia with parkinsonism linked to chromosome-17 mutations
Tubulin and microtubule structure
Downing KH and Nogales E
Current Opinion in Cell Biology, 10(1), 16-22 (1998)

商品

Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.

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