跳转至内容
Merck
CN
所有图片(1)

文件

安全信息

T3309

Sigma-Aldrich

转铁蛋白 人

≥98%

别名:

转铁蛋白,部分饱和

登录查看公司和协议定价
所有图片(1)

About This Item

CAS号:
11096-37-0
EC 号:
234-318-8
MDL编号:
MFCD00132442
UNSPSC代码:
12352202
NACRES:
NA.61

生物来源

human

质量水平

200

检测方案

≥98%

形式

powder

铁含量

300-600 ppm

技术

cell culture | stem cell: suitable

杂质

≤1.0 EU/mg endotoxin

UniProt登记号

P02787

储存温度

2-8°C

基因信息

human ... TF(7018)

正在寻找类似产品? 访问 产品对比指南

一般描述

转铁蛋白是一种分子量为80kDa的血清糖蛋白， 其半衰期为8至10天。该基因位于人染色体3q22.1上。转铁蛋白在肝细胞中表达。

应用

转铁蛋白已被用于：
  • 分离表皮干细胞和细胞扩增
  • 研究化合物处理对转铁蛋白摄取的影响
  • 转铁蛋白摄取和共聚焦成像

生化/生理作用

转铁蛋白可促进人淋巴细胞的增殖。该效果与铁含量成正比。
转铁蛋白可促进铁转运至红细胞和外周组织中。该基因的突变与转铁蛋白血症有关。转铁蛋白是胎儿发育必需的物质。它是非免疫原性的，并且转铁蛋白偶联药物可抑制心脏毒性和耐药性。

分析说明

通过琼脂糖电泳纯化。

免责声明

供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

WGK

WGK 3

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the carbohydrate content of human transferrin?

    We have found the information on transferrin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.According to the table, Transferrin is 6 percent carbohydrate, citing G.A. Jamieson, J. Biol. Chem. 240(7), 2914-2920 (1965).The table also gives information on the percentage of each type of monosaccharide that is present.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

TFRC (transferrin receptor (p90, CD71))
Dorak MT
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Severe hypochromic microcytic anemia in a patient with congenital atransferrinemia
Shamsian BS, et al.
Pediatric Hematology and Oncology, 26(5), 356-362 (2009)
Non-invasive in vivo imaging of near infrared-labeled transferrin in breast cancer cells and tumors using fluorescence lifetime FRET
Abe K, et al.
PLoS ONE, 8(11), e80269-e80269 (2013)
A Djeha et al.
British journal of haematology, 80(2), 235-241 (1992-02-01)
The effect of different forms of iron and iron-binding proteins on the proliferative response of human lymphocytes to phytohaemagglutinin (PHA) has been studied. Transferrin enhanced proliferation, the effect being proportional to the degree of iron saturation up to 100%, but
Influence of tobacco smoking on transferrin sialylation during pregnancy in smoking and non-smoking women with iron deficiency
Wrzesniak M, et al.
Environmental Toxicology and Pharmacology, 46, 95-102 (2016)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门