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Merck
CN
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文件

安全信息

T1147

Sigma-Aldrich

脱铁转铁蛋白 人

powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

别名:

人转铁蛋白, 铁传递蛋白

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About This Item

CAS号:
11096-37-0
EC 号:
234-318-8
MDL编号:
MFCD00130536
UNSPSC代码:
12352202
NACRES:
NA.75

生物来源

human plasma

质量水平

200

产品线

BioReagent

检测方案

≥98% (agarose gel electrophoresis)

形式

powder

分子量

76-81 kDa

浓度

~25 mM

技术

cell culture | mammalian: suitable

杂质

HIV and HBsAg, source material tested negative
≤0.005% iron

溶解性

H2O: 50 mg/mL

UniProt登记号

P02787

运输

wet ice

储存温度

−20°C

基因信息

human ... TF(7018)

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相关类别

应用

载脂蛋白转铁蛋白可以补充铁或用于结合培养基中存在的游离铁，还可用于将铁运输到哺乳动物细胞中。

生化/生理作用

转铁蛋白是一种存在于血清中的主要铁结合和细胞传递分子。 无血清细胞培养系统需要一种铁的传递形式。 转铁蛋白是铁的优选传递形式，因为细胞可通过细胞表面上的转铁蛋白受体以生理学上适当的方式对转铁蛋白结合的铁进行处理。 人载脂蛋白-转铁蛋白是一种高亲和力的转铁蛋白，可用于多种细胞类型。 载脂蛋白-转铁蛋白可以在使用前装载铁或直接添加到含铁介质中。

其他说明

非血红素铁转运蛋白。

免责声明

供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

WGK

WGK 3

法规信息

常规特殊物品

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the carbohydrate content of human transferrin?

    We have found the information on transferrin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.According to the table, Transferrin is 6 percent carbohydrate, citing G.A. Jamieson, J. Biol. Chem. 240(7), 2914-2920 (1965).The table also gives information on the percentage of each type of monosaccharide that is present.

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    Ask a Scientist here.

Giang D Nguyen et al.
PloS one, 8(8), e72698-e72698 (2013-08-24)
Huntington's disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored.
Kathleen N O'Guin et al.
ASN neuro, 6(1), e00135-e00135 (2014-01-31)
The molecular requirements for human myelination are incompletely defined, and further study is needed to fully understand the cellular mechanisms involved during development and in demyelinating diseases. We have established a human co-culture model to study myelination. Our earlier observations
Giang D Nguyen et al.
PloS one, 9(5), e96858-e96858 (2014-05-08)
H1 linker histone proteins are essential for the structural and functional integrity of chromatin and for the fidelity of additional epigenetic modifications. Deletion of H1c, H1d and H1e in mice leads to embryonic lethality by mid-gestation with a broad spectrum
William J Buchser et al.
PloS one, 7(6), e38101-e38101 (2012-06-16)
Trauma to the spinal cord and brain can result in irreparable loss of function. This failure of recovery is in part due to inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans (CSPGs). Peripheral nervous system (PNS) neurons exhibit
Ayumu Suzuki et al.
Nature communications, 7, 11056-11056 (2016-03-31)
Meiosis is a unique process that allows the generation of reproductive cells. It remains largely unknown how meiosis is initiated in germ cells and why non-germline cells do not undergo meiosis. We previously demonstrated that knockdown of Max expression, a
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