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Merck
CN
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文件

安全信息

T0665

Sigma-Aldrich

全转铁蛋白 人

powder, BioReagent, suitable for cell culture, ≥97%

别名:

嗜铁蛋白，铁饱和

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About This Item

CAS号:
11096-37-0
EC 号:
234-318-8
MDL编号:
MFCD00131337
UNSPSC代码:
12352202
NACRES:
NA.75

生物来源

human plasma

质量水平

200

描述

Iron-saturated

产品线

BioReagent

检测方案

≥97%

形式

powder

技术

cell culture | mammalian: suitable

杂质

HIV, HBsAg and HCV, none detected (tested by FDA approved testing methods)
 endotoxin, tested

溶解性

H2O: 50 mg/mL

UniProt登记号

P02787

运输

ambient

储存温度

2-8°C

基因信息

human ... TF(7018)

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应用

罗斯韦尔公园纪念研究所（Roswell Park Memorial Institute (RPMI)）已通过补充人全转铁蛋白进行原红细胞增殖测定，同时这种成分还被补充进培养基，以进行电感耦合等离子体发射光谱分析。
转铁蛋白是一种存在于血清中的主要铁结合和细胞传递分子。 无血清细胞培养系统需要一种铁的传递形式。 转铁蛋白是铁的优选传递形式，因为细胞可通过细胞表面上的转铁蛋白受体以生理学上适当的方式对转铁蛋白结合的铁进行处理。 人全转铁蛋白是一种高亲和性的转铁蛋白，可与多种细胞类型一起使用。 人全转铁蛋白在使用前会加载铁并可被直接添加到贫铁或无铁的细胞培养基中。

生化/生理作用

以一种生理性稳定且安全的形式向细胞提供铁。

制备说明

在60 °C（最低）经至少10小时的热处理。

分析说明

经琼脂糖凝胶电泳纯度。
通过ICP的铁含量是按批次进行报道的。

免责声明

供研究使用。在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

WGK

WGK 3

法规信息

常规特殊物品

分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the carbohydrate content of human transferrin?

    We have found the information on transferrin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.According to the table, Transferrin is 6 percent carbohydrate, citing G.A. Jamieson, J. Biol. Chem. 240(7), 2914-2920 (1965).The table also gives information on the percentage of each type of monosaccharide that is present.

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    Ask a Scientist here.

Jill M Brown et al.
Nature communications, 9(1), 3849-3849 (2018-09-23)
Self-interacting chromatin domains encompass genes and their cis-regulatory elements; however, the three-dimensional form a domain takes, whether this relies on enhancer-promoter interactions, and the processes necessary to mediate the formation and maintenance of such domains, remain unclear. To examine these
Senthil Raja Jayapal et al.
Cell cycle (Georgetown, Tex.), 15(22), 3070-3081 (2016-09-23)
Cyclin A2 is an essential gene for development and in haematopoietic stem cells and therefore its functions in definitive erythropoiesis have not been investigated. We have ablated cyclin A2 in committed erythroid progenitors in vivo using erythropoietin receptor promoter-driven Cre
Co-operative signalling mechanisms required for erythroid precursor expansion in response to erythropoietin and stem cell factor
Arcasoy O and Jiang X
British Journal of Haematology, 130(1), 121-129 (2005)
Ryohichi Sugimura et al.
Nature, 545(7655), 432-438 (2017-05-18)
A variety of tissue lineages can be differentiated from pluripotent stem cells by mimicking embryonic development through stepwise exposure to morphogens, or by conversion of one differentiated cell type into another by enforced expression of master transcription factors. Here, to
Pamela Sarkar et al.
Cytotherapy, 20(1), 21-28 (2017-09-18)
Clinical trials using ex vivo expansion of autologous mesenchymal stromal cells (MSCs) are in progress for several neurological diseases including multiple sclerosis (MS). Given that environment alters MSC function, we examined whether in vitro expansion, increasing donor age and progressive
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