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生物来源
mouse
重组
expressed in E. coli
偶联物
untagged
方案
>95% (SDS-PAGE)
表单
lyophilized
分子量
~17 kDa by SDS-PAGE
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
技术
immunohistochemistry: suitable
杂质
<0.1 EU/μg endotoxin, tested
颜色
white
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Il1b(16176)
相关类别
一般描述
白细胞介素-1β (IL-1β)由活化的巨噬细胞产生。它属于与炎症反应有关的IL-1蛋白家族。
生化/生理作用
白介素-1β (IL-1β)可通过诱导IL-2释放、B细胞成熟和增殖以及成纤维细胞生长因子活性来刺激胸腺细胞增殖。在大多数情况下，IL-1β,需要炎症小体复合物被裂解和分泌。 该蛋白可调节肠中嗜酸性粒细胞的作用。
外形
从PBS中冻干。
重悬
用100 μL去离子水重组。
其他说明
小鼠IL-1beta（aa 118-269）未加标签。
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Jung Y
Mucosal Immunology, 8(4), 930-942 (2015)
Ruojia Ma et al.
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Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are
Understanding the mechanism of IL-1? secretion.
Lopez-Castejon G and Brough D
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Dongmin Xu et al.
Experimental and therapeutic medicine, 23(1), 14-14 (2021-11-25)
Perfluorooctane sulfonate (PFOS) is a persistent pollutant that exerts toxicity and induces cardiogenesis in humans and animals. Yet, the effect of PFOS exposure on cardiac toxicity in adult rats has, to our knowledge, not been reported and the mechanism still
Hai-Lei Guo et al.
Inflammation, 44(1), 358-370 (2020-10-13)
The inflammatory response involving interleukin-1β (IL-1β) has been thought to play an important role in the development of late-phase sepsis. However, in this study, we wanted to explore the possibility of using IL-1β to improve the prognosis of sepsis by
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