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重组
expressed in baculovirus infected Sf9 cells
产品线
PRECISIO® Kinase
方案
≥70% (SDS-PAGE)
表单
buffered aqueous glycerol solution
比活
57.8-78.2 nmol/min·mg
分子量
~85 kDa
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... FLT4(2324)
一般描述
FLT4 or fms-related tyrosine kinase 4 is a tyrosine kinase receptor for vascular endothelial growth factors C and D and highly expressed in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 is a marker for lymphatic vessels and some high endothelial venules in human adult tissues and also supported the theory of the venous origin of lymphatic vessels. FLT4 plays an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
新产品
D J Dumont et al.
Science (New York, N.Y.), 282(5390), 946-949 (1998-10-30)
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGF-C stimulates the growth of lymphatic vessels through its specific lymphatic endothelial receptor VEGFR-3. Here it
A Kaipainen et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(8), 3566-3570 (1995-04-11)
We have recently cloned the human fms-like tyrosine kinase 4 gene FLT4, whose protein product is related to two vascular endothelial growth factor receptors FLT1 and KDR/FLK1. Here the expression of FLT4 has been analyzed by in situ hybridization during
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