SRP3093
IL-4 人
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
别名:
BCDF, BCGF, B细胞刺激因子（BSF-1）
产品名称
IL-4 人, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
biological source
human
recombinant
expressed in E. coli
assay
≥98% (HPLC)
≥98% (SDS-PAGE)
form
lyophilized
potency
≤0.2 ng/mL ED50
mol wt
14.9 kDa
packaging
pkg of 20 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
off-white to yellow
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL4(3565)
Application
白细胞介素-4（IL-4）已被用作小胶质细胞M2状态的刺激剂，其与伤口愈合和碎片清除有关。
Biochem/physiol Actions
IL-4是一种多效细胞因子，可调节多种T细胞和B细胞反应，包括细胞增殖、存活和基因表达。重组人IL-4是一种含有129个氨基酸残基的14.9kDa球状蛋白质。
General description
IL-4是一种多效细胞因子，其可调节多种T细胞和B细胞反应，包括细胞增殖、存活和基因表达。IL-4由肥大细胞、T细胞和骨髓基质细胞产生，可调节初始CD4+ T细胞向辅助Th2细胞的分化，该过程可通过细胞因子分泌谱进行表征，包括IL-4、IL-5、IL-6、IL-10和IL-13的分泌，其可用于体液免疫应答。IL-4的另一个主要功能是调节免疫球蛋白类别转换为IgG1和IgE同种型。Th2细胞过量产生IL-4与IgE产生和过敏增加有关。重组人IL-4是一种含有129个氨基酸残基的14.9kDa球状蛋白质。
Other Notes
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Physical form
冻干品，无添加剂。
Preparation Note
在打开之前将小瓶进行离心。用水进行重悬至浓度为0.1-1.0 mg/ml。不要涡旋。该溶液可在2-8℃下储存最长达1周。如需更长时间的储存，建议使用含有稳定剂（如5％海藻糖）的缓冲液进行进一步的稀释，并在分装成工作体积后冻存在-20°C至-80°C。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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