推荐产品
相关类别
一般描述
IL-4是一种多效细胞因子，其可调节多种T细胞和B细胞反应，包括细胞增殖、存活和基因表达。IL-4由肥大细胞、T细胞和骨髓基质细胞产生，可调节初始CD4+ T细胞向辅助Th2细胞的分化，该过程可通过细胞因子分泌谱进行表征，包括IL-4、IL-5、IL-6、IL-10和IL-13的分泌，其可用于体液免疫应答。IL-4的另一个主要功能是调节免疫球蛋白类别转换为IgG1和IgE同种型。Th2细胞过量产生IL-4与IgE产生和过敏增加有关。重组人IL-4是一种含有129个氨基酸残基的14.9kDa球状蛋白质。
应用
白细胞介素-4（IL-4）已被用作小胶质细胞M2状态的刺激剂，其与伤口愈合和碎片清除有关。
生化/生理作用
IL-4是一种多效细胞因子，可调节多种T细胞和B细胞反应，包括细胞增殖、存活和基因表达。重组人IL-4是一种含有129个氨基酸残基的14.9kDa球状蛋白质。
序列
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
外形
冻干品，无添加剂。
重悬
在打开之前将小瓶进行离心。用水进行重悬至浓度为0.1-1.0 mg/ml。不要涡旋。该溶液可在2-8℃下储存最长达1周。如需更长时间的储存，建议使用含有稳定剂（如5％海藻糖）的缓冲液进行进一步的稀释，并在分装成工作体积后冻存在-20°C至-80°C。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Lijie Li et al.
Reproductive biology and endocrinology : RB&E, 19(1), 128-128 (2021-08-26)
Endometriosis is a serious reproductive and general health consequences. Recombinant human IL-37 (rhIL-37) is an inhibitor of inflammation. ELISA assay was performed to detect the concentration of cytokines. Flow cytometry was used to analyze cell proportion. Besides, qRT-PCR and western
Interleukin-4: a prototypic immunoregulatory lymphokine.
W E Paul
Blood, 77(9), 1859-1870 (1991-05-01)
Lu Liu et al.
Journal of experimental & clinical cancer research : CR, 41(1), 358-358 (2022-12-25)
IFN-γ is a key mediator of tumor immunity that can induce macrophage polarization to suppress tumor growth. Cyclin G2 functions as a tumor suppressor in various cancer cells; however, its role in macrophages remains unclear. This study aimed to investigate
Lancelot Marique et al.
The Journal of clinical endocrinology and metabolism, 99(5), 1722-1732 (2014-01-31)
Hashimoto's thyroiditis (HT) and Graves' disease (GD) are thyroid autoimmune disorders driven by Th1 and Th2 immune responses, respectively. Caveolin-1 (Cav-1), thyroid peroxidase (TPO), and dual oxidase (DUOX) are thought to be part of the thyroxisome, which is essential to
Masanori Kobayashi et al.
Cancer immunology, immunotherapy : CII, 63(8), 797-806 (2014-04-30)
Dendritic cell (DC)-based cancer vaccines may have a significant benefit to patients with advanced pancreatic cancer. However, variations among clinical studies make it difficult to compare clinical outcomes. Here, we identified factors that determined the clinical benefits by analyzing data
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门