SRP0432
PDE4D2 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
别名:
DPDE3, PDE43, STRK1, phosphodiesterase 4D, cAMP-specific
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
≥13600 pmol/min-μg
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
产品名称
PDE4D2 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥80% (SDS-PAGE)
form
aqueous solution
specific activity
≥13600 pmol/min-μg
mol wt
84 kDa
packaging
pkg of 5 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... PDE4D(5144)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Other Notes
One unit is defined as the amount of enzyme that will convert 1 pmole of 3′, 5′-cAMP to 5′-AMP per min at 37°C in a reaction buffer.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
George S Baillie et al.
The Biochemical journal, 404(1), 71-80 (2007-02-10)
Beta2-ARs (beta2-adrenoceptors) become desensitized rapidly upon recruitment of cytosolic beta-arrestin. PDE4D5 (family 4 cAMP-specific phosphodiesterase, subfamily D, isoform 5) can be recruited in complex with beta-arrestin, whereupon it regulates PKA (cAMP-dependent protein kinase) phosphorylation of the beta2-AR. In the present
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持