生物来源
human
重组
expressed in baculovirus infected Sf9 cells
检测方案
≥90% (SDS-PAGE)
形式
aqueous solution
分子量
48 kDa (RbBP5)
51 kDa (EED)
53 kDa (AEBP2)
86 kDa (EZH2)
87 kDa (SUZ12)
包装
pkg of 20 μg
运输
dry ice
储存温度
−70°C
基因信息
human ... AEBP2(121536) , EED(8726) , EZH2(2146) , RBBP4(5928) , SUZ12(23512)
一般描述
Mutant version of EZH2 5 member complex, with a Tyr- to-His mutation on amino acids 646 of the EZH2 protein (Genbank Accession No. NM_004456). This mutation is often cited in the scientific literature as Y641H in variant 3 (GenBank Accession No. NM_001203247).
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ryan D Morin et al.
Nature genetics, 42(2), 181-185 (2010-01-19)
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribute to the activated B-cell
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