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安全信息

SRP0372

Sigma-Aldrich

MKK6 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

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别名:
MAP2K6, MEK6, mitogen-activated protein kinase kinase 6
UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

检测方案

≥80% (SDS-PAGE)

形式

aqueous solution

分子量

63.5 kDa

包装

pkg of 20 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

1.36 mg/mL

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... MAP2K6(5608)

一般描述

Human MKK6 (GenBank Accession No. NM_002758.3), amino acids 2-end with N-terminal GST-tag, MW=63.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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T L Lotan et al.
The Journal of pathology, 212(4), 386-394 (2007-06-20)
Identification of the signalling cascades that are differentially activated during prostatic tumourigenesis is a crucial step in the search for future molecular targets in this disease. The stress-activated protein kinase (SAPK) signalling cascade culminates in the phosphorylation of the JNK
Carlo Serra et al.
Molecular cell, 28(2), 200-213 (2007-10-30)
During muscle regeneration, the mechanism integrating environmental cues at the chromatin of muscle progenitors is unknown. We show that inflammation-activated MKK6-p38 and insulin growth factor 1 (IGF1)-induced PI3K/AKT pathways converge on the chromatin of muscle genes to target distinct components

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