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Merck
CN
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主要文件

安全信息

SRP0348

Sigma-Aldrich

Flt1 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

别名:

VEGFR1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

方案

≥70% (SDS-PAGE)

表单

aqueous solution

分子量

67.5 kDa

包装

pkg of 10 μg

技术

activity assay: suitable
inhibition assay: suitable

NCBI登记号

AF063657

UniProt登记号

P17948

运输

dry ice

储存温度

−70°C

基因信息

human ... FLT1(2321)

一般描述

Human Flt1 ( GenBank Accession No. AF063657), amino acids 783-end with N-terminal His-tag, MW=67.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

单位定义

One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to the tyrosine substrate per minute at pH 7.4 and 30°C.

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H315,H319,H360D

危险分类

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number
40223

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M Shibuya
The international journal of biochemistry & cell biology, 33(4), 409-420 (2001-04-20)
Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1) is structurally a typical tyrosine kinase receptor of about 180 kDa, and carries seven Ig-like domains in the extracellular region and a tyrosine kinase domain with a long kinase insert. Recent studies have revealed
N Rahimi et al.
The Journal of biological chemistry, 275(22), 16986-16992 (2000-04-05)
Vascular endothelial growth factor (VEGF) provokes angiogenesis in vivo and stimulates growth and differentiation of endothelial cells in vitro. Although VEGF receptor-1 (VEGFR-1) and VEGFR-2 are known to be high affinity receptors for VEGF, it is not clear which of

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