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主要文件

COO原产地证书/COA分析证书

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安全信息

安全和法规

SML1347

爱维莫潘

Name: 爱维莫潘
Brand: SIGMA

≥98% (HPLC)

别名:

ADL-8-2698, LY-246736, N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine

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About This Item

经验公式（希尔记法）:

C₂₅H₃₂N₂O₄

CAS号:

156053-89-3

分子量:

424.53

MDL编号:

MFCD09838268

UNSPSC代码:

12352200

PubChem化学物质编号:

329825803

NACRES:

NA.77

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1 of 10

Sigma-Aldrich

SML2956

Nalmefene Hydrochloride

Sigma-Aldrich

CDS023112

Alvimopan

Sigma-Aldrich

5.08017

nor-Binaltorphimine Dihydrochloride

S219282

6,6-DIMETHYL-3-OXO-BICYCLO(2.2.2)OCTANE-2-CARBOXYLIC ACID DIETHYLAMIDE

Sigma-Aldrich

119139

Adenosine A₃受体激动剂，2-Cl-IB-MECA

Sigma-Aldrich

AV54779

Anti-LGALS3BP antibody produced in rabbit

Sigma-Aldrich

772828

5-Norbornene-2-endo-acetic acid

Sigma-Aldrich

5.08015

CTOP

Sigma-Aldrich

282367

(1S,2S,3R,5S)-(+)-蒎烷二醇

Sigma-Aldrich

QBD10800

m-dPEG^®₈-Lipoamide

质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D +46 to +52°, c = 1.0 in DMSO

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear

储存温度

2-8°C

SMILES字符串

C[C@H]1CN(C[C@@H](C(NCC(O)=O)=O)CC2=CC=CC=C2)CC[C@]1(C3=CC=CC(O)=C3)C

InChI

1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1

InChI key

UPNUIXSCZBYVBB-JVFUWBCBSA-N

基因信息

human ... OPRM1(4988)

生化/生理作用

Alvimopan is a gastroprokinetic peripheral mu-opioid receptor antagonist.

Alvimopan is a gastroprokinetic peripheral mu-opioid receptor antagonist. As a drug, Alvimopan is given to patients undergoing bowel surgery to protect the bowel from the effects of opioid medications that are used to treat pain, blocking the undesirable GI side-effects of the opioid agonists without affecting analgesia or causing withdrawal. Alvimopan does not cross the blood-brain barrier, competitively binding to gastrointestinal tract mu-opioid receptors.