SML0468
多佐胺
≥98% (HPLC)
别名:
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, 4S,6S-Dorzolamide, L-671,152, MK-507
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关于此项目
经验公式（希尔记法）:
C10H16N2O4S3
化学文摘社编号:
分子量:
324.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1
SMILES string
CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
InChI key
IAVUPMFITXYVAF-XPUUQOCRSA-N
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -25 to -35°, c = 1 in methanol
color
white to beige
solubility
DMSO: 5 mg/mL (clear solution, warmed)
storage temp.
room temp
Quality Level
Gene Information
human ... CA2(760)
相关类别
Biochem/physiol Actions
Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
Dorzolamide is a potent carbonic anhydrase II inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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