生物来源
rabbit
质量水平
物料
colorless
克隆
9A6E2, monoclonal
表单
liquid
分子量
140 kDa
种属反应性
human
浓度
0.39 mg/mL
技术
western blot: 1:500 - 1:2000
颜色
colorless
同位素/亚型
IgG
免疫原序列
MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQL
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... HDAC4(9759)
一般描述
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC4 (P56524).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
应用
WB
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
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