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Merck
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安全信息

SAB5701990

Sigma-Aldrich

Anti-HBG1 Antibody, clone 1R9T7, Rabbit Monoclonal

别名:

HBG-T2, HBGA, HBGR, HSGGL1, PRO2979

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

物料

colorless

克隆

1R9T7, monoclonal

形式

liquid

分子量

12 kDa

种属反应性

human

浓度

1.06 mg/mL

技术

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

颜色

colorless

同位素/亚型

IgG

免疫原序列

VLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... HBG1(3047)

一般描述

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 68-147 of human HBG1 (P69891).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IF/ICC

WGK

WGK 1

法规信息

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