生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
polyclonal
形式
liquid
种属反应性
human, rat, mouse
浓度
1.09 mg/mL
技术
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pSer498)
基因信息
human ... HDAC5(10014)
一般描述
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
免疫原
A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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