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Merck
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主要文件

安全信息

SAB5600204

Sigma-Aldrich

Anti-beta-Actin antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM112, purified immunoglobulin

别名:

ACTB, Actin cytoplastic 1, actin beta, beta-actin

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

重组

expressed in HEK 293 cells

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

RM112, monoclonal
recombinant monoclonal

表单

buffered aqueous glycerol solution

种属反应性

all

技术

ChIP: 1:200
ELISA: suitable (assay dependent concentration)
flow cytometry: suitable (assay dependent concentration)
immunocytochemistry: 1:200
immunohistochemistry: 1:200
immunoprecipitation (IP): 1:200
western blot: 1:1000

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ACTB(60)

特异性

This antibody reacts to beta-Actin (Actin, cytoplasmic 1). No cross reactivity with other isoforms of Actin.

免疫原

A peptide corresponding to the N-terminus of beta-actin

外形

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Vipul K Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 349, 796-811 (2022-08-02)
We describe a role of CD44-mediated signaling during host-defense against tuberculosis (TB) using a mouse model of TB and studies in M. tuberculosis (Mtb) infected human macrophage (MФ). Liposomes targeting CD44 using thioaptamers (CD44TA-LIP) were designed and tested as new
Abhishek Mishra et al.
Frontiers in immunology, 13, 859116-859116 (2022-06-01)
GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a major role in immunity against tuberculosis (TB) infection, the mechanism
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Molecular autism, 12(1), 25-25 (2021-03-25)
One of the causal mechanisms underlying neurodevelopmental disorders (NDDs) is chromatin modification and the genes that regulate chromatin. AT-rich interactive domain 1B (ARID1B), a chromatin modifier, has been linked to autism spectrum disorder and to affect rare and inherited genetic
Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells.
Standoli, et al.
International Journal of Molecular Sciences, 24 (2023)
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Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis of primary Sjögren's syndrome (SS); however, the mechanisms sustaining SGEC activation in primary SS remain unclear. We undertook this study to determine the role of autophagy in the

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