产品名称
抗-GAPDH 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
36kDa
species reactivity
guinea pig, rat, horse, human, mouse
concentration
0.5 mg - 1 mg/mL
technique(s)
immunoblotting: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GAPDH(2597)
Application
兔抗 GAPDH 抗体可用于免疫印迹。
Biochem/physiol Actions
3-磷酸甘油醛脱氢酶（GAPDH）可催化甘油醛-磷酸盐的可逆氧化磷酸化，其碳水化合物代谢中的关键能量产生步骤。它可与几种蛋白质结合，包括肌动蛋白、微管蛋白、淀粉样蛋白前体、聚谷氨酰胺肽、DRPLA（齿状核红核苍白球丘脑下部核萎缩）和亨廷顿蛋白。磷酸化的GAPDH可与细胞骨架元件结合并控制早期分泌途径中的微管动力学。GAPDH也是功能性GAIT（干扰素γ激活的翻译抑制剂）mRNP（信使核糖核蛋白）的组分。在黑素瘤进展期间GAPDH表达失调。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
3-磷酸甘油醛脱氢酶（GAPDH）定位于细胞质中，但可根据细胞条件转移至细胞核。它是包含相同链的四聚体。编码这种蛋白的基因位于人类染色体 12p13 上。
Immunogen
指向人 GAPDH 中间区域的合成肽
Other Notes
合成肽位于以下区域：KAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNC
Physical form
在含 0.09% (w/v) 叠氮化钠和 2% 蔗糖的 1x PBS 缓冲液中提供纯化抗体。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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