跳转至内容
Merck
CN
所有图片(2)

主要文件

安全信息

SAB1410774

Sigma-Aldrich

Anti-MAOA antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 59.7 kDa

种属反应性

human

技术

western blot: 1 μg/mL

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... MAOA(4128)

一般描述

Monoamine oxidase A (MAOA) is encoded by the gene mapped to human chromosome Xp21-p11.The encoded protein is an isoform of MAO enzyme.

免疫原

MAOA (NP_000231.1, 1 a.a. ~ 527 a.a) full-length human protein.

Sequence
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS

生化/生理作用

Monoamine oxidase A (MAOA) catalyzes the degradation of biogenic amines such as dopamine, noradrenaline and serotonin. Over activation of MAOA is associated with the human heart failure (HF) pathogenesis. Thus, the protein is considered to be a potential target for the treatment of HF.{32 }Mutation in the gene leads to panic disorder (PD).

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target.
Manni ME
Oxidative Medicine and Cellular Longevity (2016)
Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment.
Haberstick BC
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 135B, 59-64 (2005)
MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy.
Reif A
Molecular Psychiatry, 19, 122-128 (2014)
Human monoamine oxidase gene (MAOA): chromosome position (Xp21-p11) and DNA polymorphism.
Ozelius L
Genomics, 3, 53-58 (1988)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门