SAB1300716
Anti-CDA (C-term) antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-CDD, Anti-Cytidine aminohydrolase, Anti-Cytidine deaminase
产品名称
Anti-CDA (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
shipped in
dry ice
biological source
rabbit
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human
technique(s)
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CDA(978)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
CDA forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in the CDA gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Immunogen
CDA (NP_001776, 123-156)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human CDA.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human CDA.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Woosuk Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(15), 4027-4032 (2016-04-02)
Deoxycytidine kinase (dCK), a rate-limiting enzyme in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positron emission tomography (PET) imaging target in cancer. PET probes for dCK have been developed and are effective in mice but have
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