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质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
protect from light
under inert gas
颜色
orange-brown
溶解性
DMSO: 12 mg/mL (orange solution)
储存温度
−20°C
SMILES字符串
CN(C)S(=O)(=O)c1ccc2NC(=O)C(=C/c3cc4CCCCc4[nH]3)\c2c1
InChI
1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-
InChI key
LOGJQOUIVKBFGH-YBEGLDIGSA-N
基因信息
human ... SRC(6714)
生化/生理作用
SU 6656是一种选择性Src家族激酶抑制剂。SU 6656可抑制CD34阳性选择的脐血细胞中的Src激酶。
特点和优势
这种化合物是激酶磷酸酶生物学研究的特色产品。点击此处发现更多特色激酶磷酸酶生物产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种:
分析证书(COA)
Pain, 158(7), 1204-1216 (2017-03-18)
We previously developed a model of opioid-induced neuroplasticity in the peripheral terminal of the nociceptor that could contribute to opioid-induced hyperalgesia, type II hyperalgesic priming. Repeated administration of mu-opioid receptor (MOR) agonists, such as DAMGO, at the peripheral terminal of
American journal of physiology. Cell physiology, 288(6), C1193-C1201 (2005-01-29)
Platelet-derived growth factor (PDGF) is an important regulator of vascular smooth muscle (VSM) cell growth and migration and has been identified as a key mediator of neointima formation resulting from vascular injury. PDGF exerts its effects, in part, through activation
Cell reports, 30(1), 9-17 (2020-01-09)
Regeneration following spinal root avulsion is broadly unsuccessful despite the regenerative capacity of other PNS-located nerves. By combining focal laser lesioning to model root avulsion in zebrafish, time-lapse imaging, and transgenesis, we identify that regenerating DRG neurons fail to recapitulate
Oncogenesis, 9(1), 6-6 (2020-02-01)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood cancer. There are no immunotherapies and few molecularly targeted therapeutics available for treatment of this malignancy. The identification and characterization of genes and pathways that drive T-ALL progression are critical for
Science advances, 6(17), eaaz3154-eaaz3154 (2020-06-05)
The sodium leak channel (NALCN) is essential for survival in mammals: NALCN mutations are life-threatening in humans and knockout is lethal in mice. However, the basic functional and pharmacological properties of NALCN have remained elusive. Here, we found that robust
商品
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
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