精脒

一氧化氮合酶(nNOS)参与一氧化氮的生成。

Spermidine, a natural biomolecule, is known for its wide-ranging health benefits, including anti-inflammatory effects, antioxidant properties, and improvements in respiratory function. It carries a positive charge at physiological pH, allowing it to interact with oppositely charged DNA and RNA. Dietary intake of spermidine is associated with a reduced risk of neurodegeneration, metabolic diseases, heart ailments, and cancer. Spermidine-induced autophagy has been shown to slow the rate of cognitive decline by clearing amyloid-beta plaques in the brain. Spermidine supplementation improves mitochondrial metabolism and translational activity. Moreover, spermidine exhibits cell-autonomous effects on cancer cells and influences their communication with immune effectors, leading to the acceleration of tumor-associated antigen identification and cancer cell death. Spermidine-mediated autophagy inhibits the activation of apoptosis in cancer cells and is linked to tissue development and cell differentiation. This natural compound is additionally recognized for its neuroprotective, and anti-aging properties and is naturally found in semen, as well as in various plant sources.

亚精胺已可用于：

• 制备5x转录缓冲液
• 与其他试剂一起处理双链RNA以增加线虫对dsRNA的摄取
• 作为大鼠脑多胺分析研究的标准(185)

抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA，可用于DNA结合蛋白纯化。激活T₄聚核苷酸激酶活性。

如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。

惰性气体中保存。空气敏感；强吸湿性。