产品名称
大鼠BDNF ELISA试剂盒, for cell culture supernatants, plasma, and serum samples
species reactivity
human, rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Bdnf(24225)
Application
仅供研究使用。不可用于诊断操作。
详细内容请参阅附件实验方案。
详细内容请参阅附件实验方案。
Biochem/physiol Actions
脑源性神经营养因子（BDNF）参与人类的海马功能和言语情节记忆。BDNF在血管功能中也起着至关重要的作用，并通过特异性受体原肌球蛋白相关激酶B（TrkB）参与血管生成。它参与了阿尔茨海默′病的发病机制。
General description
脑源性神经营养因子（BDNF）基因定位于人类染色体11p14.1上。该基因编码前体蛋白proBDNF。成熟的BDNF（mBDNF）是通过proBDNF的翻译后切割合成的。
该ELISA抗体对可检测大鼠和人BDNF。其他物种尚未测定。
Other Notes
本产品提供了样品检验报告。请在批号对应的文本框中输入样品一词。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Jie Kang et al.
Brain sciences, 11(1) (2020-12-31)
(1) Background: Depression is one of the overwhelming public health problems. Alleviating hippocampus injury may prevent depression development. Herein, we established the chronic unpredictable mild stress (CUMS) model and aimed to investigate whether aerobic exercise (AE) could alleviate CUMS induced
Peripheral vascular reactivity and serum BDNF responses to aerobic training are impaired by the BDNF Val66Met polymorphism.
Lemos JR Jr, et al.
Physiological Genomics, 48(2), 116-123 (2015)
Irina Naletova et al.
International journal of molecular sciences, 22(24) (2021-12-25)
l-carnosine (β-alanyl-l-histidine) (Car hereafter) is a natural dipeptide widely distributed in mammalian tissues and reaching high concentrations (0.7-2.0 mM) in the brain. The molecular features of the dipeptide underlie the antioxidant, anti-aggregating and metal chelating ability showed in a large
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Egan MF, et al.
Cell, 112(2), 257-269 (2003)
11p14. 1 microdeletions associated with ADHD, autism, developmental delay, and obesity.
Shinawi M, et al.
American Journal of Medical Genetics. Part A, 155(6), 1272-1280 (2011)
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