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Merck
CN

RAB0634

Sigma-Aldrich

人TNNI3 /肌钙蛋白I,心肌ELISA试剂盒

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 100 pg/mL
standard curve range: 125-8000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... TNNI3(7137)

一般描述

人心肌肌钙蛋白(TNNI3)ELISA试剂盒用于定量测定细胞培养上清、血浆和血清中的肌钙蛋白I。

应用

仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)

生化/生理作用

心肌肌钙蛋白I(cTnI)与扩张型心肌病相关,病理表现为左心室扩张,收缩能力下降。cTnI与心肌肌钙蛋白T和C共同组成肌钙蛋白复合体。cTnI可抑制肌动蛋白-肌球蛋白的相互作用。它通过影响Ca2+敏感度参与肌节激活。cTnI也可作为心肌损伤标志物。

其他说明

本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Changting Cui et al.
Journal of translational medicine, 16(1), 236-236 (2018-08-31)
Major differences exist between men and women in both physiology and pathophysiology. Dissecting the underlying processes and contributing mechanisms of sex differences in health and disease represents a crucial step towards precision medicine. Considering the significant differences between men and
Bangwei Wu et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(2), 713-728 (2017-06-16)
Mitochondrial DNA (mtDNA), acting as a newly found 'danger-associated molecular patterns' (DAMPs), is released into circulation upon tissue injury and performs as a considerable activator of inflammation and immune response. However, the role of circulating mtDNA in experimental autoimmune myocarditis
George Techiryan et al.
Circulation research, 123(8), 986-995 (2018-10-26)
Metformin has been demonstrated to decrease infarct size (IS) and prevent postinfarction left ventricular (LV) remodeling in rodents when given intravenously at the time of reperfusion. It remains unclear whether similar cardioprotection can be achieved in a large animal model.
Nicholas Chun et al.
PloS one, 12(6), e0179450-e0179450 (2017-07-01)
The pathophysiology of myocardial injury that results from cardiac ischemia and reperfusion (I/R) is incompletely understood. Experimental evidence from murine models indicates that innate immune mechanisms including complement activation via the classical and lectin pathways are crucial. Whether factor B
Genotype-specific pathogenic effects in human dilated cardiomyopathy
Bollen IA, et al.
The Journal of Physiology, 595(14), 4677-4693 (2017)

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