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NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... FGF1(2246)
Input:
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/mL
standard curve range: 16.38-4000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF1(2246)
General description
FGF1 (fibroblast growth factor 1) gene encodes a member of the fibroblast growth factor (FGF) family. It encodes a pro-angiogenic protein that is ubiquitously expressed. In humans, FGF1 is alternatively spliced into four forms: FGF1A (in kidney), FGF1B (in brain), FGF1-C and -D (in vascular smooth muscle cells and fibroblasts). This gene is located on human chromosome 5q31.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
FGF1 (fibroblast growth factor 1) is mainly involved in cell growth, proliferation and neurogenesis. It also participates in wound healing, post-ischemic heart repair and making of collaterals after hindlimb ischemia. FGF1 functions as an angiogenic factor that participates in tissue repair, carcinogenesis and maintenance of vasculature stability.
The FGF1 ELISA kit provides for the quantitative measurement of Fibroblast Growth Factor 1 in Cell Culture Supernatants, Plasma and Serum.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yash Chhabra et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6412-6430 (2019-02-20)
Growth hormone (GH) has an important function as an insulin antagonist with elevated insulin sensitivity evident in humans and mice lacking a functional GH receptor (GHR). We sought the molecular basis for this sensitivity by utilizing a panel of mice
Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis.
Li R, et al.
Genetics and molecular research : GMR, 14(3), 11191-11199 (2015)
Regulation of FGF1 gene promoter through transcription factor RFX1.
Hsu YC, et al.
The Journal of Biological Chemistry (2010)
Daniel Chiumia et al.
International journal of molecular sciences, 21(5) (2020-03-01)
Fibroblast growth factors (FGF) play an important role during embryo development. To date, the role of FGF and the respective receptors (FGFR) during the preimplantation phase in cattle are not fully characterized. We examined FGF1, FGF2, FGFR1, FGFR2, and FGFR3
Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
Kirov A, et al.
PLoS ONE, 7(5), e36485-e36485 (2012)
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