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安全信息

RAB0537

Sigma-Aldrich

人FABP2 /脂肪酸结合蛋白,肠道ELISA试剂盒

for serum, plasma, cell culture supernatants and urine

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UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type plasma
sample type serum
sample type urine
sample type cell culture supernatant(s)

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 25 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... FABP2(2169)

一般描述

该试剂盒提供的抗体对可检测血清、血浆、细胞培养上清液和尿液中的人肠型脂肪酸结合蛋白。

脂肪酸结合蛋白(FABP2)是由定位于人类染色体4q28–q31的基因编码的细胞内蛋白质。主要分布于肠上皮细胞。FABP2基因编码肠型FABP蛋白(I-FABP)。

应用

仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)

生化/生理作用

脂肪酸结合蛋白(FABP2)在膳食长链脂肪酸的吸收和细胞内转运中起着重要作用。也支持脂肪酸代谢。FABP2可能是糖尿病和胰岛素抵抗的候选基因。还参与脂质代谢和脂肪生成。

其他说明

本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.
Furuhashi M and Gokhan S H
Nature Reviews. Drug Discovery, 7(6), 489-489 (2008)
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Dysfunction of the gut-blood barrier plays an important role in many diseases, such as inflammatory bowel disease, hemorrhagic shock (HS), or burn injury. However, little is known about gut barrier dysfunction after hemodynamically instable polytrauma (PT). Therefore, we aimed to
Marina Saresella et al.
Frontiers in immunology, 11, 1390-1390 (2020-08-01)
Background: Butyric acid (BA) is a short-chain fatty acid (SCFA) with anti-inflammatory properties, which promotes intestinal barrier function. Medium-chain fatty acids (MCFA), including caproic acid (CA), promote TH1 and TH17 differentiation, thus supporting inflammation. Aim: Since most SCFAs are absorbed
Stefan P Kastl et al.
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Acute heart failure and cardiogenic shock are associated with an impaired intestinal perfusion, which may lead to a release of cytoplasmatic proteins by hypoxic epithelial injury. Intestinal fatty acid binding protein (iFABP), highly specific for the small bowel enterocyte, may
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T follicular helper (Tfh) cells are crucial for B cell differentiation and antigen-specific antibody production. Dysregulation of Tfh-mediated B cell help weakens B cell responses in HIV infection. Moreover, Tfh cells in the lymph node and peripheral blood comprise a

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