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主要文件

安全信息

RAB0480

Sigma-Aldrich

大鼠肿瘤坏死因子α ELISA试剂盒

for cell and tissue lysates

别名:

TNF-α

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选择尺寸

1 G
CN¥1,006.32
5 G
CN¥3,242.74
25 G
CN¥11,849.43

CN¥1,006.32

目录价CN¥1,597.73节省 37%

国内现货,预计发货时间April 27, 2025详情



选择尺寸

变更视图
1 G
CN¥1,006.32
5 G
CN¥3,242.74
25 G
CN¥11,849.43

About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

CN¥1,006.32

目录价CN¥1,597.73节省 37%

国内现货,预计发货时间April 27, 2025详情


种属反应性

rat

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 25 pg/mL
standard curve range: 82.3-20000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

rat ... Tnf(24835)

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此商品
D063243816D5545
grade

for molecular biology

grade

-

grade

for molecular biology

grade

-

assay

≥99.5% (RT)

assay

≥98% (HPLC), ≥99.0% (titration)

assay

900-1100 mmol/L (Titration molarity)

assay

≥99.0% (titration)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

product line

BioUltra

product line

-

product line

BioUltra

product line

BioXtra

form

powder

form

powder

form

liquid

form

powder

mp

41-44 °C (lit.)

mp

41-44 °C (lit.)

mp

-

mp

41-44 °C (lit.)

一般描述

大鼠 TNF-α ELISA(酶联免疫吸附测定)试剂盒是定量测定细胞裂解液和组织裂解液中大鼠 TNF-α 的一种体外酶联免疫测定法。

免疫原

重组大鼠 TNF-α

应用

仅限研究用途,不可用于诊断。
大鼠肿瘤坏死因子 α ELISA 试剂盒已用于测定细胞裂解液和组织裂解物中的大鼠肿瘤坏死-α(TNF-α)的浓度。[1][2]

生化/生理作用

肿瘤坏死因子-α(TNF-α)影响脑损伤后的血脑屏障、炎症、血栓形成和血管变化等各种细胞过程。TNF-α 的表达在阿尔茨海默病、多发性硬化症、帕金森氏病、脑膜炎球菌性脑膜炎和 HIV 感染等各种中枢神经系统疾病中上调。脑和血液中 TNF-α 表达上调(响应脂多糖)可能会使得高血压大鼠的脑干血栓形成和出血以及中风敏感性/风险增加。[3]肿瘤坏死因子-α 激活多形核白细胞 NADPH 氧化酶,从而促进大鼠全身性氧化应激(OS)、炎症和高血压的发生。[4]

其他说明

本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)化学品安全说明书

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)化学品安全说明书

  • RABLYSIS12X Cell Lysis Buffer (Item J)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  • RABWASH420X Wash Buffer (Item B)

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

法规信息

常规特殊物品
含少量动物源组分生物产品
  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    访问文档库

    Hanaa Mohamed Khalaf et al.
    Clinical and experimental hepatology, 5(1), 65-74 (2019-03-28)
    Non-alcoholic fatty liver disease (NAFLD) is a challenging health problem. Hyperuricemia is a key player in the pathogenesis of NAFLD. This study investigated the effect of allopurinol (uric acid synthesis inhibitor) in combination with metformin and vitamin E in prevention
    R A Ajala-Lawal et al.
    Archives of physiology and biochemistry, 126(2), 107-115 (2018-10-06)
    This study investigated the influence of betulinic acid on high-fructose diet-induced metabolic syndrome in rats. Oral administration of betulinic acid significantly reversed high-fructose diet-mediated increase in body mass index and blood glucose. Furthermore, betulinic acid restored high-fructose diet-mediated alterations in
    Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.
    Mazor R
    Hypertension, 55(2), 353-362 (2010)
    Meijuan Chen et al.
    Gastroenterology research and practice, 2019, 8723460-8723460 (2019-10-01)
    Phosphatidylcholine (PC) is the major surface-active phospholipid and creates a hydrophobic nature to the surface. It has been reported to reverse the progression of liver fibrosis and to improve liver function. The aim of the present study was to evaluate
    Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy.
    Ahmed S
    Inflammation, 39(5), 1783-1797 (2016)

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