产品名称
人 IL-1 β ELISA 试剂盒, for serum, plasma, cell culture supernatant and urine
storage temp.
−20°C
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 pg/mL
standard curve range: 0.48-100 pg/mL
detection method
colorimetric
shipped in
wet ice
Gene Information
human ... IL1B(3553)
Application
仅供研究使用。不可用于诊断操作。
人 IL-1 β ELISA试剂盒已被用于测定细胞培养上清液中白细胞介素1β (IL-1 β)的浓度。
人 IL-1 β ELISA试剂盒已被用于测定细胞培养上清液中白细胞介素1β (IL-1 β)的浓度。
Biochem/physiol Actions
白细胞介素1β (IL-1 β)是一种促炎细胞因子，其可诱导多种急性和慢性炎症。因此，IL1B被认为是与纤维化和组织重塑相关的疾病的潜在治疗靶标。 IL-1β 蛋白会增加内源性92kDa明胶酶（基质金属蛋白酶9（MMP-9））和MMP组织抑制剂（TIMP-1）的产生。 滑液中IL-1β 浓度的升高会促进滑膜炎的发病，以及颞下颌关节软骨组织和骨的退行性变化。 IL-1β 可将中性粒细胞和巨噬细胞带到感染部位。 IL-1β 基因突变与Henoch-Schönlein紫癜(HSP)的肾脏表现和肾脏后遗症有关。
General description
人IL-1 β ELISA（酶联免疫吸附测定）试剂盒采用体外酶联免疫吸附测定法，定量测定人血清、血浆、细胞培养物上清液和尿液中的IL-1 β含量。
Immunogen
重组人IL-1β
Other Notes
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
低风险生物材料
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