种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 pg/mL
standard curve range: 0.48-100 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... IL1B(3553)
一般描述
人IL-1 β ELISA(酶联免疫吸附测定)试剂盒采用体外酶联免疫吸附测定法,定量测定人血清、血浆、细胞培养物上清液和尿液中的IL-1 β含量。
免疫原
重组人IL-1β
应用
仅供研究使用。不可用于诊断操作。
人 IL-1 β ELISA试剂盒已被用于测定细胞培养上清液中白细胞介素1β (IL-1 β)的浓度。
人 IL-1 β ELISA试剂盒已被用于测定细胞培养上清液中白细胞介素1β (IL-1 β)的浓度。
生化/生理作用
白细胞介素1β (IL-1 β)是一种促炎细胞因子,其可诱导多种急性和慢性炎症。因此,IL1B被认为是与纤维化和组织重塑相关的疾病的潜在治疗靶标。 IL-1β 蛋白会增加内源性92kDa明胶酶(基质金属蛋白酶9(MMP-9))和MMP组织抑制剂(TIMP-1)的产生。 滑液中IL-1β 浓度的升高会促进滑膜炎的发病,以及颞下颌关节软骨组织和骨的退行性变化。 IL-1β 可将中性粒细胞和巨噬细胞带到感染部位。 IL-1β 基因突变与Henoch-Schönlein紫癜(HSP)的肾脏表现和肾脏后遗症有关。
其他说明
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语:
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
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