RAB0205
人 GDNF ELISA 试剂盒
for serum, plasma, cell culture supernatant and urine
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... GDNF(2668)
Input:
sample type serum
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
产品名称
人 GDNF ELISA 试剂盒, for serum, plasma, cell culture supernatant and urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type urine
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GDNF(2668)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Glial cell derived neurotrophic factor (GDNF) is a neurotrophic factor involved in dopaminergic and neurodevelopment. It plays a vital role in self-renewal of stem cells. In addition, GDNF also facilitates differentiation of chained undifferentiated spermatogonia. GDNF with its receptors, activates various signaling pathways essential for maintaining cellular homeostasis. Mutated gene is associated with the development of schizophrenia. GDNF is a potential target for treating Parkinson′s disease.
General description
Glial cell derived neurotrophic factor (GDNF) is encoded by the gene mapped to human chromosome 5p14.1−q13.3. It belongs to the transforming growth factor β (TGF-β) superfamily. GDNF is abundantly found in gliomas.
Immunogen
Recombinant Human GDNF
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia
Williams HJ, et al.
Schizophrenia Research, 97(1-3), 271-276 (2007)
The reversible effects of glial cell line--derived neurotrophic factor (GDNF) in the human brain
Ayanlaja A, et al.
Seminars in Cancer Biology, 53(3), 212-222 (2018)
Liliana Brambilla et al.
Human molecular genetics, 25(14), 3080-3095 (2016-06-12)
Considerable evidence indicates that neurodegeneration in amyotrophic lateral sclerosis (ALS) can be conditioned by a deleterious interplay between motor neurons and astrocytes. Astrocytes are the major glial component in the central nervous system (CNS) and fulfill several activities that are
Wenxing Zhao et al.
Neuroscience letters, 637, 108-113 (2016-11-27)
Inflammatory and neurotrophic factors are involved in postherpetic neuralgia (PHN), but the association of these factors in the cerebrospinal fluid (CSF) with the level of pain is poorly known. The present study aimed to examine the changes in neurotrophic and
Distribution of GFRA1-expressing spermatogonia in adult mouse testis
Grasso M, et al.
Reproduction (Cambridge, England), 143(3) (2012)
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