种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.78-2000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... CSF1(1435)
一般描述
M-CSF (colony stimulating factor 1) is a pleiotropic macrophage growth factor. It has a signal peptide, a 149-amino acid receptor-binding domain, a variable spacer region and a transmembrane region with a cytoplasmic tail. The human M-CSF receptor is a 972-amino acid glycosylated protein which consist of an extracellular region made of five immunoglobulin-like domains (D1–D5), a transmembrane region and an intracellular autocatalytic kinase domain. This gene is mapped to human chromosome p13-p21.
The Human MCSF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MCSF in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human MCSF
应用
请参考Protocol了解详情。
生化/生理作用
M-CSF (colony stimulating factor 1) plays a major role in the immune response, bone metabolism and the development of some cancers. It modulates macrophage survival, proliferation, differentiation and chemotaxis.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
新产品
Reassignment of the human CSF1 gene to chromosome 1p13-p21.
Morris SW, et al.
Blood, 78(8), 2013-2020 (1991)
Combinatorial and computational approaches to identify interactions of macrophage colony-stimulating factor (M-CSF) and its receptor c-FMS.
Rosenfeld L, et al.
The Journal of Biological Chemistry, 290(43), 26180-26193 (2015)
Teresa Di Desidero et al.
Pharmacological research, 158, 104920-104920 (2020-05-29)
Anaplastic thyroid cancer (ATC) is a rare neoplasia with a poor prognosis. Proliferation and apoptosis assays were performed on ATC cell lines (8305C, 8505C) exposed to vinorelbine, lenvatinib, as well as to concomitant combinations. ABCB1, ABCG2 and CSF-1 mRNA expression
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门