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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.066-16 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... BDNF(627)
一般描述
人 BDNF ELISA(酶联免疫吸附试验)试剂盒是一种体外酶联免疫吸附试验,用于定量测定血清、血浆、细胞培养上清液和尿液中的人 BDNF。
脑源性神经营养因子(BDNF)基因定位于人类染色体 11p14.1 上。BDNF是生长因子中神经营养蛋白家族的成员,该 该基因编码前体蛋白proBDNF。成熟的BDNF(mBDNF)是通过proBDNF的翻译后切割合成的。proBDNF 和 mBDNF 在细胞信号传导中都起着至关重要的作用。
免疫原
重组人 BDNF
应用
人BDNF ELISA试剂盒已用于:
- 测定脑源性神经营养因子(BDNF)蛋白表达
- 测定脑片培养基和器官型脑片培养(OBSC)提取物中的BDNF水平
- 测定血浆BDNF水平
仅供研究使用。用于诊断程序。
人 BDNF ELISA 试剂盒已用于确定骨髓间充质干细胞 (MSC) 移植对 Tourette 综合征 (TS) 大鼠纹状体中 BDNF 蛋白表达的影响。 也用于测定 GD1(高雪氏病 1 类型)患者和对照人群的血浆 BDNF 水平。
人 BDNF ELISA 试剂盒已用于确定骨髓间充质干细胞 (MSC) 移植对 Tourette 综合征 (TS) 大鼠纹状体中 BDNF 蛋白表达的影响。 也用于测定 GD1(高雪氏病 1 类型)患者和对照人群的血浆 BDNF 水平。
生化/生理作用
脑源性神经营养因子(BDNF)参与人类的海马功能和言语情节记忆。因此,BDNF 基因表达的变异会改变这些神经功能。BDNF在血管功能中也起着至关重要的作用,并通过特异性受体原肌球蛋白相关激酶B(TrkB)参与血管生成。它参与了阿尔茨海默′病的发病机制。ProBDNF 与 p75 神经营养因子受体相互作用,导致海马体的长期抑制。
其他说明
本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。
请在批号对应的文本框中输入样品 一词。
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语:
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
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