所有图片(1)
About This Item
经验公式（希尔记法）:
C27H25F2N3OS
CAS号:
分子量:
477.57
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
形式
powder
颜色
white
溶解性
methanol: >10 mg/mL
DMSO: >10.1 mg/mL
2-hydroxypropyl-β-cyclodextrin: insoluble
H2O: insoluble
dilute aqueous base: insoluble
SMILES字符串
CC1=C(CCN2CCC(\CC2)=C(\c3ccc(F)cc3)c4ccc(F)cc4)C(=O)N5C=CSC5=N1
InChI
1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3
InChI key
JUQLTPCYUFPYKE-UHFFFAOYSA-N
基因信息
human ... HTR2A(3356)
rat ... Adra1a(29412) , Drd2(24318) , Htr1a(24473) , Htr2a(29595) , Htr7(65032)
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应用
利坦色林已用于行为测试，并用作 5-羟色胺 2A 受体（5-HT2A）受体拮抗剂。
生化/生理作用
利坦色林是有效的 5-羟色胺 2A 受体（5-HT2A）羟色胺受体拮抗剂/反向激动剂，可穿过血脑屏障。它调节 5-HT 2A 受体，并被认为具有抗帕金森作用。利坦色林还通过调节情绪、认知和消极症状来影响精神分裂症。
有效的 5-HT2A 5-羟色胺受体拮抗剂/反向激动剂，可穿越血脑屏障。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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