P8891
溴丙胺太林
≥97% (TLC), powder
别名:
(2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate
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关于此项目
线性分子式:
C23H30NO3Br
化学文摘社编号:
分子量:
448.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352111
EC Number:
200-030-6
MDL number:
产品名称
溴丙胺太林, ≥97% (TLC), powder
InChI key
XLBIBBZXLMYSFF-UHFFFAOYSA-M
InChI
1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
SMILES string
[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C
assay
≥97% (TLC)
form
powder
color
white to off-white
solubility
H2O: 50 mg/mL
originator
Shire
Quality Level
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
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Biochem/physiol Actions
Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.
Features and Benefits
This compound was developed by Shire. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
P Alberts
The Journal of pharmacology and experimental therapeutics, 274(1), 458-468 (1995-07-01)
The experiments were done to investigate the presence and subtype of functionally presynaptic muscarinic receptors in cholinergic nerves of the guinea pig urinary bladder. Bladder strips were incubated with 3H-choline and superfused with Tyrode's solution containing eserine. Secreted 3H-acetylcholine was
S Alaranta et al.
British journal of pharmacology, 101(2), 472-476 (1990-10-01)
1. The relative potency in blocking the nicotine-induced relaxation of the bovine retractor penis muscle (BRP) was estimated for 12 drugs known to have ganglion-blocking properties. 2. The order of potency of the drugs studied was mecamylamine greater than chlorisondamine
F Xavier Donadeu et al.
Biology of reproduction, 91(5), 111-111 (2014-09-26)
Several aspects of equine ovarian physiology are unique among domestic species. Moreover, follicular growth patterns are very similar between horses and humans. This study aimed to characterize, for the first time, global gene expression profiles associated with growth and preovulatory
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