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Merck
CN

P7123

Sigma-Aldrich

Protein Kinase Cν (PKCν) Active human

recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution

别名:

PKD3, Protein Kinase C nu

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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32

重组

expressed in E. coli

质量水平

方案

≥75% (SDS-PAGE)

表单

buffered aqueous glycerol solution

分子量

protein apparent mol wt ~142 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PRKD3(23683)

应用

Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 °C using a final concentration of 50 μM [32P] ATP.

生化/生理作用

PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.

外形

Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol

储存分类代码

10 - Combustible liquids

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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