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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
lyophilized powder
种属反应性
human, rat
技术
immunohistochemistry: suitable
western blot: suitable
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... P2RY1(5028)
rat ... P2ry1(25265)
一般描述
嘌呤能受体 P2Y1是G 蛋白偶联受体的成员。 P2Y1 基因定位于人染色体3q25.2。它存在于心脏、血管、前列腺、睾丸、卵巢和神经组织中。
免疫原
对应于大鼠或人P2Y1残基242-258的合成肽。
应用
兔内产生的抗嘌呤能受体 P2Y1抗体已用于免疫印迹（稀释度1:200）和免疫组化（稀释度1:50）。
生化/生理作用
嘌呤能受体 P2Y1 可用作细胞外 ATP 和 ADP 的受体。它对于 ADP 诱导的血小板活化、聚集和血栓形成至关重要。P2Y1还参与基于内皮细胞的核苷酸诱导松弛和钙动员。它是产生新的抗血小板化合物和抗炎策略的潜在靶标。
外形
从1%牛血清白蛋白和0.05%叠氮化钠的磷酸盐缓冲盐水（pH 7.4）中冻干。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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