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Merck
CN

P6149

Sigma-Aldrich

黄体酮

γ-irradiated, BioXtra, suitable for cell culture

别名:

4-孕烯-3,20-二酮

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About This Item

经验公式(希尔记法):
C21H30O2
CAS号:
分子量:
314.46
Beilstein:
1915950
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.77
生物来源:
synthetic (organic)
表单:
powder
方案:
≥99%

生物来源

synthetic (organic)

质量水平

描述

synthesized from materials derived from plant source

无菌性

γ-irradiated

产品线

BioXtra

方案

≥99%

表单

powder

效能

0.1-20 ng/mL

技术

cell culture | mammalian: suitable

mp

128-132 °C (lit.)

溶解性

chloroform: 50 mg/mL, clear, colorless to light yellow

运输

ambient

储存温度

room temp

SMILES字符串

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

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应用

可用于细胞培养应用中研究固醇对细胞信号传导和基因表达的调节。

生化/生理作用

诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。 孕激素与乳腺癌发病有关。

其他说明

黄体分泌的类固醇激素。

外形

粉末(室温);(储备液)按使用分量分成小份冻存,以避免使用时反复冻融

重悬

添加1 ml纯酒精,轻轻晃动使其溶解,再添加49 ml无菌培养基,制备获得20 μg/ml储备液。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 2 - Lact. - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Pediatric endocrinopathies are commonly diagnosed and monitored by measuring hormones of the hypothalamic-pituitary-gonadal axis. Because growth and development can markedly influence normal circulating concentrations of fertility hormones, accurate reference intervals established on the basis of a healthy, nonhospitalized pediatric population
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Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)
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Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase

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