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质量水平
方案
98-101%
表单
powder
mp
210 °C (dec.) (lit.)
溶解性
H2O: 100 mg/mL
作用机制
cell wall synthesis | interferes
储存温度
2-8°C
SMILES字符串
CC(C)(S)[C@@H](N)C(O)=O
InChI
1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1
InChI key
VVNCNSJFMMFHPL-VKHMYHEASA-N
基因信息
mouse ... Oprk1(18387)
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一般描述
D-青霉胺来源于相应的 β-内酰胺抗生素的水解。
应用
在肝豆状核变性病中用作抗风湿药和螯合剂。用作铜螯合剂与半胱氨酸或其他硫化物介质组分形成混合二硫化物。用于灭活蛋白-1dna 结合 ，抑制兔关节软骨细胞异步培养的生长 。
生化/生理作用
青霉胺是青霉素类抗生素的特征性降解产物。一个铜原子与两个青霉胺分子结合。青霉胺可减少胱氨酸尿症中过量胱氨酸的排泄。这是通过青霉胺和胱氨酸之间的二硫键互换，形成易于排泄的青霉胺-半胱氨酸二硫化物。青霉胺可干扰原胶原分子之间交联的形成，并在新形成时将其裂解。青霉胺降低 IgM 类风湿因子，抑制 T 细胞活性。
其他说明
将容器密闭保存在干燥和通风良好的地方。
警示用语：
Warning
危险声明
危险分类
Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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