形式
liquid
质量水平
浓度
0.5% in propylene glycol
λmax
0.40-1.00 at 506-520 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
InChI
1S/C26H24N4O/c1-16-9-10-17(2)22(13-16)27-28-23-14-19(4)24(15-18(23)3)29-30-26-21-8-6-5-7-20(21)11-12-25(26)31/h5-15,29H,1-4H3/b28-27?,30-26-
InChI key
HJAYEODIXUYVIC-LTFAAIOASA-N
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一般描述
油红 O 染色并赋予脂质红橙色。据报道，它还能标记在急性淋巴细胞白血病（ALL-L3）或伯基特淋巴瘤/白血病中观察到的空泡。需对新鲜样品进行油红 O 染色，因为酒精固定可去除脂质。
应用
油红 O 溶液已被用于鉴定 3T3-L1 细胞系脂肪细胞上的胞质内脂滴并测量 Simpson-Golabi-Behmel 综合征（SGBS）前脂肪细胞中的脂质含量。
油红O是一种脂溶性偶氮染料，用于对冷冻切片的中性甘油三酯和脂质以及石蜡切片的一些脂蛋白进行染色。在组织学中，以异丙醇为溶剂的油红O过饱和溶液可用于对组织中的脂肪染色。
WGK
WGK 3
闪点(°F)
217.4 °F
闪点(°C)
103 °C
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Alyssa M Flores et al.
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Atherosclerosis is the process that underlies heart attack and stroke. A characteristic feature of the atherosclerotic plaque is the accumulation of apoptotic cells in the necrotic core. Prophagocytic antibody-based therapies are currently being explored to stimulate the phagocytic clearance of
Jesse W Williams et al.
Nature immunology, 21(10), 1194-1204 (2020-09-09)
Early atherosclerosis depends upon responses by immune cells resident in the intimal aortic wall. Specifically, the healthy intima is thought to be populated by vascular dendritic cells (DCs) that, during hypercholesterolemia, initiate atherosclerosis by being the first to accumulate cholesterol.
Bingning Dong et al.
Hepatology (Baltimore, Md.), 71(5), 1559-1574 (2019-09-12)
Obesity-induced chronic inflammation is a key component in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and insulin resistance. Increased secretion of proinflammatory cytokines by macrophages in metabolic tissues promotes disease progression. In the diet-induced obesity (DIO) mouse model, activation
LWW Doody's all reviewed collection, McClatchey: Clinical Laboratory Medicine
Clinical Laboratory Medicine (2002)
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