跳转至内容

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

N8768

Sigma-Aldrich

Natriuretic Peptide, C-Type

≥95% (HPLC)

别名:

CNP

登录查看公司和协议定价

选择尺寸

1 L
¥945.70
2.5 L
¥2,007.65
4 L
¥3,258.68

¥945.70

预计发货时间2025年7月07日详情

获取大包装报价
所有图片(1)

选择尺寸

变更视图
1 L
¥945.70
2.5 L
¥2,007.65
4 L
¥3,258.68

About This Item

经验公式（希尔记法）:
C93H157N27O28S3
CAS号:
127869-51-6
分子量:
2197.60
MDL编号:
MFCD00080348
UNSPSC代码:
12352200
PubChem化学物质编号:
329818688
NACRES:
NA.77

¥945.70

预计发货时间2025年7月07日详情

获取大包装报价

质量水平

200

方案

≥95% (HPLC)

表单

powder

组成

Peptide content, ≥65%

UniProt登记号

P23582

储存温度

−20°C

SMILES字符串

CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CN

InChI

1S/C93H157N27O28S3/c1-12-52(10)76-91(146)104-42-72(127)108-65(44-122)88(143)114-57(26-30-149-11)82(137)118-64(43-121)80(135)103-39-70(125)106-58(31-48(2)3)78(133)101-41-74(129)110-68(92(147)148)47-151-150-46-67(109-73(128)40-100-77(132)54(23-16-18-27-94)111-89(144)66(45-123)119-85(140)59(32-49(4)5)105-69(124)37-96)90(145)116-62(35-53-21-14-13-15-22-53)79(134)102-38-71(126)107-60(33-50(6)7)84(139)112-55(24-17-19-28-95)81(136)115-61(34-51(8)9)86(141)117-63(36-75(130)131)87(142)113-56(83(138)120-76)25-20-29-99-93(97)98/h13-15,21-22,48-52,54-68,76,121-123H,12,16-20,23-47,94-96H2,1-11H3,(H,100,132)(H,101,133)(H,102,134)(H,103,135)(H,104,146)(H,105,124)(H,106,125)(H,107,126)(H,108,127)(H,109,128)(H,110,129)(H,111,144)(H,112,139)(H,113,142)(H,114,143)(H,115,136)(H,116,145)(H,117,141)(H,118,137)(H,119,140)(H,120,138)(H,130,131)(H,147,148)(H4,97,98,99)/t52-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,76-/m0/s1

InChI key

UHSBKBYWHCBDCJ-DYGWFTAGSA-N

基因信息

human ... NPPC(4880)

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
101786101775100915
Petroleum benzine boiling range 40-60°C for gas chromatography ECD and FID SupraSolv®

101772

Petroleum benzine boiling range 40-60°C

Petroleum benzine boiling range 30-50°C for analysis EMSURE®

101786

Petroleum benzine boiling range 30-50°C

Petroleum benzine for analysis boiling range 40-60°C EMSURE® ACS,ISO

101775

Petroleum benzine

Petroleum benzine boiling range to about 40°C EMPLURA®

100915

Petroleum benzine

technique(s)

gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

200

form

liquid

form

liquid

form

liquid

form

liquid

mp

<-80 °C

mp

-

mp

<-80 °C

mp

-

expl. lim.

0.8-7.4 % (v/v)

expl. lim.

1.2-7.5 % (v/v)

expl. lim.

1.0-7.4 % (v/v)

expl. lim.

1.3-7.8 % (v/v)

bp

40-60 °C/1013 hPa

bp

30-50 °C/1013 hPa

bp

36-83 °C/1013 hPa

bp

<40 °C/1013 hPa

Amino Acid Sequence

Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys [Disulfide Bridge: 6-22]

一般描述

Natriuretic Peptide, C-Type (NPPC/ CNP) is a 22 amino acid peptide encoded by NPPC gene mapped to human chromosome 2q37.1.[1] It belongs to the natriuretic peptide family.[2]

生化/生理作用

C-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and most major endocrine glands. It has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function.
Natriuretic Peptide, C-Type (NPC) plays a vital role in regulation of blood pressure and body fluid homeostasis. NPC-mediated signaling is essential for endochondral ossification.[1] NPC acts as a ligand for natriuretic peptide receptor B (NPR-B).[3] NPC interacts with receptors on vascular smooth muscle cells (VSMCs) and functions as an autocrine/paracrine endothelium-derived hormone.[3] It is also implicated in the endothelial dysfunction and regulation of adipogenesis, which has a crucial role in the development of obesity in childhood.[4] NPC has potential as a marker for obesity and bone injury induced by steroid hormones.[4][5] In vitro studies show that NPC is involved in the inhibition of smooth muscle cell proliferation, natriuresis, diuresis, vasodilation and inhibition of the renin- angiotensin system. NPC is associated with the development of myocardial infarction and heart failure. Plasma NPC levels can be used as a biomarker for the therapeutic efficacy of metoprolol on postural tachycardia syndrome (POTS) in children.[5]

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    SLCJ8259
    SLCF0284
    SLCC3506
    SLCB2292
    SLBS8363

    没有发现合适的版本？

    如果您需要特殊版本，可通过批号或批次号查找具体证书。

    搜索COA

    已有该产品？

    在文件库中查找您最近购买产品的文档。

    访问文档库

    A cluster of translocation breakpoints in 2q37 is associated with overexpression of NPPC in patients with a similar overgrowth phenotype.
    Moncla A
    Human Mutation, 28(12), 118-118 (2007)
    Kyung-Bon Lee et al.
    Biology of reproduction, 88(2), 42-42 (2012-12-21)
    Natriuretic peptide type C (NPPC) and its receptor natriuretic peptide receptor 2 (NPR2) regulate cGMP in ovarian follicles and participate in maintaining oocyte meiotic arrest. We investigated the regulation of Nppc expression in mouse granulosa cells in vivo and in
    C-type natriuretic peptide is closely associated to obesity in Caucasian adolescents.
    Del Ry S
    Clinica Chimica Acta; International Journal of Clinical Chemistry, 460, 172-177 (2016)
    Fanny Caputo et al.
    Scientific reports, 7(1), 4636-4636 (2017-07-07)
    Cerium oxide nanoparticles (CNPs) are novel synthetic antioxidant agents proposed for treating oxidative stress-related diseases. The synthesis of high-quality CNPs for biomedical applications remains a challenging task. A major concern for a safe use of CNPs as pharmacological agents is
    Y Takei
    International review of cytology, 194, 1-66 (1999-09-24)
    The natriuretic peptide (NP) system consists of three types of hormones [atrial NP (ANP), brain or B-type NP (BNP), and C-type NP (CNP)] and three types of receptors [NP receptor (R)-A, NPR-B, and NPR-C]. ANP and BNP are circulating hormones
    查看所有相关文献

    我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持