N7787
NS3694
≥98%, powder
别名:
4-Chloro-2-[3-(3-trifluoromethyl-phenyl)-ureido]benzoic acid
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关于此项目
经验公式（希尔记法）:
C15H10ClF3N2O3
化学文摘社编号:
分子量:
358.70
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
NS3694, ≥98%, powder
InChI
1S/C15H10ClF3N2O3/c16-9-4-5-11(13(22)23)12(7-9)21-14(24)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H,22,23)(H2,20,21,24)
SMILES string
OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F
InChI key
GNCZTZCPXFDPLI-UHFFFAOYSA-N
assay
≥98%
form
powder
solubility
DMSO: soluble 22 mg/mL
H2O: insoluble <5 mg/mL
storage temp.
2-8°C
Quality Level
Gene Information
human ... GRIK1(2897)
Application
NS3694 may be used as an apoptosis inhibitor to study the relationship between the cellular mechanisms controlled by amputation-induced myeloid lineage activity.
Biochem/physiol Actions
NS3694 can prevent the active apoptosome complex formation.
NS3694 is an Inhibitor of apoptosome formation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Jovany J Franco et al.
Molecular biology of the cell, 30(16), 1890-1899 (2019-02-21)
Epithelial wound healing requires a complex orchestration of cellular rearrangements and movements to restore tissue architecture and function after injury. While it is well known that mechanical forces can affect tissue morphogenesis and patterning, how the biophysical cues generated after
Cindy X Kha et al.
Experimental eye research, 169, 38-47 (2018-01-23)
Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported
Ulrik Lademann et al.
Molecular and cellular biology, 23(21), 7829-7837 (2003-10-16)
The release of mitochondrial proapoptotic proteins into the cytosol is the key event in apoptosis signaling, leading to the activation of caspases. Once in the cytosol, cytochrome c triggers the formation of a caspase-activating protein complex called the apoptosome, whereas
Developmental dependence for functional eye regrowth in Xenopus laevis.
Cindy X Kha et al.
Neural regeneration research, 13(10), 1735-1737 (2018-08-24)
Can Aztekin et al.
Development (Cambridge, England), 147(3) (2020-01-29)
Regeneration-competent vertebrates are considered to suppress inflammation faster than non-regenerating ones. Hence, understanding the cellular mechanisms affected by immune cells and inflammation can help develop strategies to promote tissue repair and regeneration. Here, we took advantage of naturally occurring tail
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