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关于此项目
经验公式(希尔记法):
C15H10ClF3N2O3
化学文摘社编号:
分子量:
358.70
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C15H10ClF3N2O3/c16-9-4-5-11(13(22)23)12(7-9)21-14(24)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H,22,23)(H2,20,21,24)
SMILES string
OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F
InChI key
GNCZTZCPXFDPLI-UHFFFAOYSA-N
assay
≥98%
form
powder
solubility
DMSO: soluble 22 mg/mL, H2O: insoluble <5 mg/mL
storage temp.
2-8°C
Quality Level
Gene Information
human ... GRIK1(2897)
Application
NS3694 may be used as an apoptosis inhibitor to study the relationship between the cellular mechanisms controlled by amputation-induced myeloid lineage activity.
Biochem/physiol Actions
NS3694 can prevent the active apoptosome complex formation.
NS3694 is an Inhibitor of apoptosome formation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported
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Epithelial wound healing requires a complex orchestration of cellular rearrangements and movements to restore tissue architecture and function after injury. While it is well known that mechanical forces can affect tissue morphogenesis and patterning, how the biophysical cues generated after
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The release of mitochondrial proapoptotic proteins into the cytosol is the key event in apoptosis signaling, leading to the activation of caspases. Once in the cytosol, cytochrome c triggers the formation of a caspase-activating protein complex called the apoptosome, whereas
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Epithelial tissues require the removal and replacement of damaged cells to sustain a functional barrier. Dying cells provide instructive cues that can influence surrounding cells to proliferate, but how these signals are transmitted to their healthy neighbors to control cellular
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