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Merck
CN

N7787

Sigma-Aldrich

NS3694

≥98%, powder

别名:

4-Chloro-2-[3-(3-trifluoromethyl-phenyl)-ureido]benzoic acid

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About This Item

经验公式(希尔记法):
C15H10ClF3N2O3
分子量:
358.70
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

方案

≥98%

表单

powder

溶解性

DMSO: soluble 22 mg/mL
H2O: insoluble <5 mg/mL

储存温度

2-8°C

SMILES字符串

OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F

InChI

1S/C15H10ClF3N2O3/c16-9-4-5-11(13(22)23)12(7-9)21-14(24)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H,22,23)(H2,20,21,24)

InChI key

GNCZTZCPXFDPLI-UHFFFAOYSA-N

基因信息

human ... GRIK1(2897)

应用

NS3694 may be used as an apoptosis inhibitor to study the relationship between the cellular mechanisms controlled by amputation-induced myeloid lineage activity.

生化/生理作用

NS3694 can prevent the active apoptosome complex formation.
NS3694 is an Inhibitor of apoptosome formation.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Jovany J Franco et al.
Molecular biology of the cell, 30(16), 1890-1899 (2019-02-21)
Epithelial wound healing requires a complex orchestration of cellular rearrangements and movements to restore tissue architecture and function after injury. While it is well known that mechanical forces can affect tissue morphogenesis and patterning, how the biophysical cues generated after
Cindy X Kha et al.
Experimental eye research, 169, 38-47 (2018-01-23)
Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported
Developmental dependence for functional eye regrowth in Xenopus laevis.
Cindy X Kha et al.
Neural regeneration research, 13(10), 1735-1737 (2018-08-24)
Ulrik Lademann et al.
Molecular and cellular biology, 23(21), 7829-7837 (2003-10-16)
The release of mitochondrial proapoptotic proteins into the cytosol is the key event in apoptosis signaling, leading to the activation of caspases. Once in the cytosol, cytochrome c triggers the formation of a caspase-activating protein complex called the apoptosome, whereas
Can Aztekin et al.
Development (Cambridge, England), 147(3) (2020-01-29)
Regeneration-competent vertebrates are considered to suppress inflammation faster than non-regenerating ones. Hence, understanding the cellular mechanisms affected by immune cells and inflammation can help develop strategies to promote tissue repair and regeneration. Here, we took advantage of naturally occurring tail

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