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N7261

去甲替林 盐酸盐

≥98% (HPLC), norepinephrine and serotonin inhibitor, powder

别名:

3-（10,11-二氢-5 H -二苯并[ a , d ] 环庚烯-5-亚基）- N -甲基-1-丙胺 盐酸盐, 去甲阿米替林 盐酸盐

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关于此项目

经验公式（希尔记法）:
C19H21N · HCl
化学文摘社编号:
894-71-3
分子量:
299.84
NACRES:
NA.77
PubChem Substance ID:
24278107
UNSPSC Code:
41116107
EC Number:
212-973-0
MDL number:
MFCD00058024
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
200
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产品名称

去甲替林 盐酸盐, ≥98% (HPLC), powder

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

ethanol: 100 mg/mL, H2O: soluble

originator

Eli Lilly

SMILES string

Cl.CNCC\C=C1\c2ccccc2CCc3ccccc13

InChI

1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H

InChI key

SHAYBENGXDALFF-UHFFFAOYSA-N

Gene Information

human ... HTR2A(3356), HTR2B(3357), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

Biochem/physiol Actions

与 5-羟色胺转运体 (K i = 161 nM) 相比，三环类抗抑郁药是去甲肾上腺素转运体 (K i = 3.4 nM) 的一种更强效的抑制剂。5-HT 2 5-羟色胺受体拮抗剂。

Features and Benefits

该化合物收录于 受体分类和信号转导手册的《生物胺转运体 》页面。想要浏览手册的其他页面， 请单击此处。
该化合物由Eli Lilly开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF8100V
BCCG7796
BCCG2928
BCBT1140
BCBN0630V

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Fabrice Gritti et al.
Journal of chromatography. A, 1282, 58-71 (2013-02-21)
The adsorption behaviors of a neutral (caffeine) and a positively charged compound (nortriptylinium) are investigated on two RPLC/hybrid stationary phases, eluted with a low ionic strength buffer (phosphate buffer, W(S)pH 2.63, I=10mM). The first phase, bridge ethylene hybrid (BEH), is
Rudolf Uher et al.
Depression and anxiety, 29(12), 1043-1049 (2012-08-31)
It has been suggested that clinician-rated scales and self-report questionnaires may be interchangeable in the measurement of depression severity, but it has not been tested whether clinically significant information is lost when assessment is restricted to either clinician-rated or self-report
Matthew T Olson et al.
Clinical chemistry, 59(6), 920-927 (2013-02-22)
The addition of a calibration curve with every run is both time-consuming and expensive for clinical mass spectrometry assays. We present alternative calibration strategies that eliminate the need for a calibration curve except as required by laboratory regulations. We measured
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全球贸易项目编号

货号GTIN
N7261-10G04061834117940