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N0761

烟酸

Name: 烟酸
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

别名:

3-吡啶甲酸, 吡啶-3-羧酸, 尼亚生, 抗糙皮病因子, 维生素 B₃

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关于此项目

经验公式（希尔记法）:

C₆H₅NO₂

化学文摘社编号:

59-67-6

分子量:

123.11

UNSPSC Code:

12352207

NACRES:

NA.71

PubChem Substance ID:

24897443

EC Number:

200-441-0

Beilstein/REAXYS Number:

109591

MDL number:

MFCD00006391

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属性

product line

BioReagent

Quality Level

200

assay

≥98%

form

powder

mol wt

M_w 123.11 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

pH

3.4 (20 °C, 10 g/L)

mp

236-239 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

density

1.473 g/cm³ at 25 °C

application(s)

agriculture

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

说明

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pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

379.4 °F - closed cup

flash_point_c

193 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000494000

0000489836

0000477443

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Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial.

Koon K Teo et al.

Stroke, 44(10), 2688-2693 (2013-07-25)

In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental

Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes).

John R Guyton et al.

Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)

This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a

Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials.

Martina Lukasova et al.

Trends in pharmacological sciences, 32(12), 700-707 (2011-09-29)

Nicotinic acid (niacin) has been used for decades to prevent and treat atherosclerosis. The well-documented antiatherogenic activity is believed to result from its antidyslipidemic effects, which are accompanied by unwanted effects, especially a flush. There has been renewed interest in

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全球贸易项目编号

货号	GTIN
N0761-100G	04061834093060