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检测方案
≥95% (HPLC)
≥95% (enzymatic)
≥95% (spectrophotometric assay)
质量水平
形式
powder
储存温度
−20°C
SMILES字符串
[Na].NC(=O)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O
InChI
1S/C21H28N7O14P2.Na.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;
InChI key
GSZRXOXBGUIRAU-UHFFFAOYSA-N
基因信息
human ... ESR1(2099) , ESR2(2100)
生化/生理作用
β-烟酰胺腺嘌呤二核苷酸 (NAD+)和β-还原烟酰胺腺嘌呤二核苷酸(NADH)组成辅酶氧化还原对(NAD+:NADH),参与广泛的酶催化氧化还原反应。 另外,在氧化还原反应中,NAD+/NADH是ADP核糖化(ADP-核糖基转移酶;聚(ADP-核酸酶)聚合酶 )反应中的ADP-核酸酶单元供体。
其他说明
本品是普通型 NAD。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Aims: The human apoptosis-inducing factor (hAIF) supports OXPHOS biogenesis and programmed cell death, with missense mutations producing neurodegenerative phenotypes.
Cell metabolism, 31(4), 809-821 (2020-03-19)
NADH provides electrons for aerobic ATP production. In cells deprived of oxygen or with impaired electron transport chain activity, NADH accumulation can be toxic. To minimize such toxicity, elevated NADH inhibits the classical NADH-producing pathways: glucose, glutamine, and fat oxidation.
Nucleic acids research, 49(20), 11596-11613 (2021-11-02)
Using the programmable RNA-sequence binding domain of the Pumilio protein, we FLAG-tagged Xist (inactivated X chromosome specific transcript) in live mouse cells. Affinity pulldown coupled to mass spectrometry was employed to identify a list of 138 candidate Xist-binding proteins, from
The EMBO journal, 40(8), e105268-e105268 (2021-02-03)
Mitochondrial translation dysfunction is associated with neurodegenerative and cardiovascular diseases. Cells eliminate defective mitochondria by the lysosomal machinery via autophagy. The relationship between mitochondrial translation and lysosomal function is unknown. In this study, mitochondrial translation-deficient hearts from p32-knockout mice were
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